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Caroline Barbara Terwee, John Devin Peipert, Robert Chapman, Jin‐Shei Lai, Berend Terluin, David F Cella, Pip Griffiths, Lidwine Brigitta Mokkink
We define the minimal important change (MIC) as a threshold for a minimal within-person change over time above which patients perceive themselves importantly changed. There is a lot of confusion about the concept of MIC, particularly about the concepts of minimal important change and minimal detectable change, which questions the validity of published MIC values. The aims of this study were: (1) to clarify the concept of MIC and how to use it; (2) to provide practical guidance for estimating methodologically sound MIC values; and (3) to improve the applicability of PROMIS by summarizing the available evidence on plausible PROMIS MIC values. We discuss the concept of MIC and how to use it and provide practical guidance for estimating MIC values. In addition, we performed a systematic review in PubMed on MIC values of any PROMIS measure from studies using recommended approaches. A total of 50 studies estimated the MIC of a PROMIS measure, of which 19 studies used less appropriate methods. MIC values of the remaining 31 studies ranged from 0.1 to 12.7 T-score points. We recommend to use the predictive modeling method, possibly supplemented with the vignette-based method, in future MIC studies. We consider a MIC value of 2-6 T-score points for PROMIS measures reasonable to assume at this point. For surgical interventions a higher MIC value might be appropriate. We recommend more high-quality studies estimating MIC values for PROMIS.
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Terwee, C. B., Peipert, J. D., Chapman, R., Lai, J., Terluin, B., Cella, D. F., Griffiths, P., & Mokkink, L. B. (2021). Minimal important change (MIC): a conceptual clarification and systematic review of MIC estimates of PROMIS measures. Quality of Life Research, 30(10), 2729–2754. https://doi.org/10.1007/s11136-021-02925-y
Terwee, Caroline Barbara, et al. "Minimal important change (MIC): a conceptual clarification and systematic review of MIC estimates of PROMIS measures." Quality of Life Research, vol. 30, no. 10, 2021, pp. 2729–2754, https://doi.org/10.1007/s11136-021-02925-y.
Terwee, Caroline Barbara, John Devin Peipert, Robert Chapman, Jin‐Shei Lai, Berend Terluin, David F Cella, Pip Griffiths, and Lidwine Brigitta Mokkink. "Minimal important change (MIC): a conceptual clarification and systematic review of MIC estimates of PROMIS measures." Quality of Life Research 30, no. 10 (2021): 2729–2754. https://doi.org/10.1007/s11136-021-02925-y.
Terwee C. B., Peipert J. D., Chapman R. [и др.] Minimal important change (MIC): a conceptual clarification and systematic review of MIC estimates of PROMIS measures // Quality of Life Research. — 2021. — Vol. 30, № 10. — P. 2729–2754. — URL: https://doi.org/10.1007/s11136-021-02925-y
@article{terwee2021minimal,
title = {{Minimal important change (MIC): a conceptual clarification and systematic review of MIC estimates of PROMIS measures}},
author = {Caroline Barbara Terwee and John Devin Peipert and Robert Chapman and Jin‐Shei Lai and Berend Terluin and David F Cella and Pip Griffiths and Lidwine Brigitta Mokkink},
journal = {Quality of Life Research},
year = {2021},
volume = {30},
number = {10},
pages = {2729--2754},
doi = {10.1007/s11136-021-02925-y},
url = {https://doi.org/10.1007/s11136-021-02925-y}
}TY - JOUR AU - Terwee, Caroline Barbara AU - Peipert, John Devin AU - Chapman, Robert AU - Lai, Jin‐Shei AU - Terluin, Berend AU - Cella, David F AU - Griffiths, Pip AU - Mokkink, Lidwine Brigitta TI - Minimal important change (MIC): a conceptual clarification and systematic review of MIC estimates of PROMIS measures JO - Quality of Life Research VL - 30 IS - 10 SP - 2729 EP - 2754 PY - 2021 DA - 2021/07/10 DO - 10.1007/s11136-021-02925-y UR - https://doi.org/10.1007/s11136-021-02925-y ER -
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