One connector, four scholarly indexes, real DOIs and legal free PDFs. Works in Claude and ChatGPT.
Paste it into Claude or ChatGPT as a custom connector. 3-day free trial.
Yumin Wang, Yumin Wang, Yongming Chen, Junjing Zhang, Yihui Yang, Joshua S. Fleishman, Yan Wang, Yan Wang, Jinhua Wang, Jichao Chen, Yuanfang Li, Hongquan Wang
Cuproptosis is a newly identified form of cell death driven by copper. Recently, the role of copper and copper triggered cell death in the pathogenesis of cancers have attracted attentions. Cuproptosis has garnered enormous interest in cancer research communities because of its great potential for cancer therapy. Copper-based treatment exerts an inhibiting role in tumor growth and may open the door for the treatment of chemotherapy-insensitive tumors. In this review, we provide a critical analysis on copper homeostasis and the role of copper dysregulation in the development and progression of cancers. Then the core molecular mechanisms of cuproptosis and its role in cancer is discussed, followed by summarizing the current understanding of copper-based agents (copper chelators, copper ionophores, and copper complexes-based dynamic therapy) for cancer treatment. Additionally, we summarize the emerging data on copper complexes-based agents and copper ionophores to subdue tumor chemotherapy resistance in different types of cancers. We also review the small-molecule compounds and nanoparticles (NPs) that may kill cancer cells by inducing cuproptosis, which will shed new light on the development of anticancer drugs through inducing cuproptosis in the future. Finally, the important concepts and pressing questions of cuproptosis in future research that should be focused on were discussed. This review article suggests that targeting cuproptosis could be a novel antitumor therapy and treatment strategy to overcome cancer drug resistance.
Formatted from the source metadata, not typed by hand. For a whole reference list, use the citation generator or ask your assistant through Find Research.
Wang, Y., Wang, Y., Chen, Y., Zhang, J., Yang, Y., Fleishman, J. S., Wang, Y., Wang, Y., Wang, J., Chen, J., Li, Y., & Wang, H. (2023). Cuproptosis: A novel therapeutic target for overcoming cancer drug resistance. Drug Resistance Updates, 72, 101018. https://doi.org/10.1016/j.drup.2023.101018
Wang, Yumin, et al. "Cuproptosis: A novel therapeutic target for overcoming cancer drug resistance." Drug Resistance Updates, vol. 72, 2023, pp. 101018, https://doi.org/10.1016/j.drup.2023.101018.
Wang, Yumin, Yumin Wang, Yongming Chen, Junjing Zhang, Yihui Yang, Joshua S. Fleishman, Yan Wang, et al. "Cuproptosis: A novel therapeutic target for overcoming cancer drug resistance." Drug Resistance Updates 72 (2023): 101018. https://doi.org/10.1016/j.drup.2023.101018.
Wang Y., Wang Y., Chen Y. [и др.] Cuproptosis: A novel therapeutic target for overcoming cancer drug resistance // Drug Resistance Updates. — 2023. — Vol. 72. — P. 101018. — URL: https://doi.org/10.1016/j.drup.2023.101018
@article{wang2023cuproptosis,
title = {{Cuproptosis: A novel therapeutic target for overcoming cancer drug resistance}},
author = {Yumin Wang and Yumin Wang and Yongming Chen and Junjing Zhang and Yihui Yang and Joshua S. Fleishman and Yan Wang and Yan Wang and Jinhua Wang and Jichao Chen and Yuanfang Li and Hongquan Wang},
journal = {Drug Resistance Updates},
year = {2023},
volume = {72},
pages = {101018},
doi = {10.1016/j.drup.2023.101018},
url = {https://doi.org/10.1016/j.drup.2023.101018}
}TY - JOUR AU - Wang, Yumin AU - Wang, Yumin AU - Chen, Yongming AU - Zhang, Junjing AU - Yang, Yihui AU - Fleishman, Joshua S. AU - Wang, Yan AU - Wang, Yan AU - Wang, Jinhua AU - Chen, Jichao AU - Li, Yuanfang AU - Wang, Hongquan TI - Cuproptosis: A novel therapeutic target for overcoming cancer drug resistance JO - Drug Resistance Updates VL - 72 SP - 101018 PY - 2023 DA - 2023/11/11 DO - 10.1016/j.drup.2023.101018 UR - https://doi.org/10.1016/j.drup.2023.101018 ER -
Add Find Research to Claude or ChatGPT and ask in plain language. The assistant reads this record, finds the papers around it and cites only what it actually found:
Setup takes about a minute: add the connector, then start the free trial.
Record from OpenAlex; open-access location from Unpaywall and the indexes. Find Research links only to legal copies.