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Thiruchelvi Pulingam, Thaigarajan Parumasivam, Amirah Mohd Gazzali, Azlinah Mohd Sulaiman, Jiun Yee Chee, Manoj Lakshmanan, Chai Fung Chin, Kumar Sudesh
Antibiotic resistance is a major health concern globally and has been estimated to cause 10 million deaths worldwide by year 2050 if the current trend of inappropriate and excessive use of antibiotics continues. Although, the discovery of antibiotics has saved countless of lives for the past 80 years, increasing levels of bacterial resistance to antibiotics would jeopardize the progress in clinical and agricultural sectors and may cause life-threatening situations even for previously treatable bacterial infections. Antibiotic resistance would increase the levels of poverty of low-middle income countries mostly due to extended hospital stays, higher cost of treatment and untimely deaths that directly affect the total productivity rate. Recent incidences of antibiotic resistance have been gradually increasing globally and this may potentiate horizontal transmission of the resistant gene and have been linked with cross-resistance to other antibiotic families as well. This review summarizes the global burden of antibiotic resistance from the economic viewpoint, highlights the recent incidences of antibiotic resistance mainly related to Escherichia coli, Acinetobacter baumannii, Klebsiella pneumoniae, Salmonella spp. and Staphylococcus aureus, describes the common mechanistic actions of antibiotic resistance and potential strategies to overcome antibiotic resistance.
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Pulingam, T., Parumasivam, T., Gazzali, A. M., Sulaiman, A. M., Chee, J. Y., Lakshmanan, M., Chin, C. F., & Sudesh, K. (2021). Antimicrobial resistance: Prevalence, economic burden, mechanisms of resistance and strategies to overcome. European Journal of Pharmaceutical Sciences, 170, 106103. https://doi.org/10.1016/j.ejps.2021.106103
Pulingam, Thiruchelvi, et al. "Antimicrobial resistance: Prevalence, economic burden, mechanisms of resistance and strategies to overcome." European Journal of Pharmaceutical Sciences, vol. 170, 2021, pp. 106103, https://doi.org/10.1016/j.ejps.2021.106103.
Pulingam, Thiruchelvi, Thaigarajan Parumasivam, Amirah Mohd Gazzali, Azlinah Mohd Sulaiman, Jiun Yee Chee, Manoj Lakshmanan, Chai Fung Chin, and Kumar Sudesh. "Antimicrobial resistance: Prevalence, economic burden, mechanisms of resistance and strategies to overcome." European Journal of Pharmaceutical Sciences 170 (2021): 106103. https://doi.org/10.1016/j.ejps.2021.106103.
Pulingam T., Parumasivam T., Gazzali A. M. [и др.] Antimicrobial resistance: Prevalence, economic burden, mechanisms of resistance and strategies to overcome // European Journal of Pharmaceutical Sciences. — 2021. — Vol. 170. — P. 106103. — URL: https://doi.org/10.1016/j.ejps.2021.106103
@article{pulingam2021antimicrobial,
title = {{Antimicrobial resistance: Prevalence, economic burden, mechanisms of resistance and strategies to overcome}},
author = {Thiruchelvi Pulingam and Thaigarajan Parumasivam and Amirah Mohd Gazzali and Azlinah Mohd Sulaiman and Jiun Yee Chee and Manoj Lakshmanan and Chai Fung Chin and Kumar Sudesh},
journal = {European Journal of Pharmaceutical Sciences},
year = {2021},
volume = {170},
pages = {106103},
doi = {10.1016/j.ejps.2021.106103},
url = {https://doi.org/10.1016/j.ejps.2021.106103}
}TY - JOUR AU - Pulingam, Thiruchelvi AU - Parumasivam, Thaigarajan AU - Gazzali, Amirah Mohd AU - Sulaiman, Azlinah Mohd AU - Chee, Jiun Yee AU - Lakshmanan, Manoj AU - Chin, Chai Fung AU - Sudesh, Kumar TI - Antimicrobial resistance: Prevalence, economic burden, mechanisms of resistance and strategies to overcome JO - European Journal of Pharmaceutical Sciences VL - 170 SP - 106103 PY - 2021 DA - 2021/12/20 DO - 10.1016/j.ejps.2021.106103 UR - https://doi.org/10.1016/j.ejps.2021.106103 ER -
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