One connector, four scholarly indexes, real DOIs and legal free PDFs. Works in Claude and ChatGPT.
Paste it into Claude or ChatGPT as a custom connector. 3-day free trial.
Andrea H. Ramirez, Lina Mahmoud Sulieman, David J. Schlueter, Alese E. Halvorson, Jun Qian, Francis Ratsimbazafy, Roxana Loperena, Kelsey Mayo, Melissa Basford, Nicole A. Deflaux and 159 more
Importance The All of Us Research Program hypothesizes that accruing one million or more diverse participants engaged in a longitudinal research cohort will advance precision medicine and ultimately improve human health. Launched nationally in 2018, to date All of Us has recruited more than 345,000 participants. All of Us plans to open beta access to researchers in May 2020. Objective To demonstrate the quality, utility, and diversity of the All of Us Research Program’s initial data release and beta launch of the cloud-based analysis platform, the cloud-based Researcher Workbench. Evidence We analyzed the initial All of Us data release, comprising surveys, physical measurements (PM), and electronic health record (EHR) data, to characterize All of Us participants including self-reported descriptors of diversity. Data depth, density, and quality were evaluated using medication sequencing analyses for depression and type 2 diabetes. Replication of known oncologic associations with smoking exposure ascertained by EHR and survey data and calculation of population-based atherosclerotic cardiovascular disease risk scores demonstrated the utility of data and platform capability. Findings The beta launch of the All of Us Researcher Workbench contains data on 224,143 participants. Seventy-seven percent of this cohort were identified as Underrepresented in Biomedical Research (UBR) including over forty-eight percent self-reporting non-White race. Medication usage patterns in common diseases depression and type 2 diabetes replicated prior findings previously reported in the literature and showed differences based on race. Oncologic associations with smoking were replicated and effect sizes compared for EHR and survey exposures finding general agreement. A cardiovascular disease score was calculated utilizing multiple data elements curated across sources. The cloud-based architecture built in the Researcher Workbench provided secure access and powerful computational resources at a low cost. All analyses have been made available for replication and reuse by registered researchers. Conclusions and Relevance The All of Us Research Program’s initial release of cohort data contains longitudinal and multidimensional data on diverse participants that replicate known associations. This dataset and the cloud-based Researcher Workbench advance the mission of All of Us to make data widely and securely available to researchers to improve human health and advance precision medicine.
Formatted from the source metadata, not typed by hand. For a whole reference list, use the citation generator or ask your assistant through Find Research.
Ramirez, A. H., Sulieman, L. M., Schlueter, D. J., Halvorson, A. E., Qian, J., Ratsimbazafy, F., Loperena, R., Mayo, K., Basford, M., Deflaux, N. A., Muthuraman, K., Natarajan, K., Kho, A., Xu, H., Wilkins, C. H., Anton‐Culver, H., Boerwinkle, E., Cicek, M. S., Clark, C. R., … Zwick, M. E. (2022). The All of Us Research Program: Data quality, utility, and diversity. Patterns, 3(8), 100570. https://doi.org/10.1016/j.patter.2022.100570
Ramirez, Andrea H., et al. "The All of Us Research Program: Data quality, utility, and diversity." Patterns, vol. 3, no. 8, 2022, pp. 100570, https://doi.org/10.1016/j.patter.2022.100570.
Ramirez, Andrea H., Lina Mahmoud Sulieman, David J. Schlueter, Alese E. Halvorson, Jun Qian, Francis Ratsimbazafy, Roxana Loperena, et al. "The All of Us Research Program: Data quality, utility, and diversity." Patterns 3, no. 8 (2022): 100570. https://doi.org/10.1016/j.patter.2022.100570.
Ramirez A. H., Sulieman L. M., Schlueter D. J. [и др.] The All of Us Research Program: Data quality, utility, and diversity // Patterns. — 2022. — Vol. 3, № 8. — P. 100570. — URL: https://doi.org/10.1016/j.patter.2022.100570
@article{ramirez2022research,
title = {{The All of Us Research Program: Data quality, utility, and diversity}},
author = {Andrea H. Ramirez and Lina Mahmoud Sulieman and David J. Schlueter and Alese E. Halvorson and Jun Qian and Francis Ratsimbazafy and Roxana Loperena and Kelsey Mayo and Melissa Basford and Nicole A. Deflaux and Karthik Muthuraman and Karthik Natarajan and Abel Kho and Hua Xu and Consuelo Hopkins Wilkins and Hoda Anton‐Culver and Eric Boerwinkle and Mine S. Cicek and Cheryl R. Clark and Elizabeth Cohn and Lucila Ohno-Machado and Sheri Dixon Schully and Brian Kenneth Ahmedani and Maria Argos and Robert Michael Cronin and Christopher J. O’Donnell and Mona N. Fouad and David B. Goldstein and Philip Greenland and Scott Joseph Hebbring and Elizabeth W. Karlson and Parinda Khatri and Bruce Korf and Jordan W. Smoller and Stephen Olufemi Sodeke and JOHN T. WILBANKS and Justin Hentges and Stephen C. Mockrin and Chris Lunt and Stephanie A. Devaney and Kelly A. Gebo and Joshua C. Denny and Robert J. Carroll and David Glazer and Paul A. Harris and George M. Hripcsak and Anthony Philippakis and Dan M. Roden and Dan M. Roden and Brian Kenneth Ahmedani and Christine D. Cole Johnson and Habib Ahsan and Donna Antoine‐LaVigne and Glendora Singleton and Hoda Anton-Culver and Eric J. Topol and Katie Baca-Motes and Steven R. Steinhubl and James C. Wade and Mark J. Begale and Praduman Jain and Scott Sutherland and Beth Lewis and Bruce R. Korf and Melissa Behringer and Ali G. Gharavi and David B. Goldstein and George M. Hripcsak and Louise Bier and Eric Boerwinkle and Murray H. Brilliant and Narayana S. Murali and Scott Joseph Hebbring and Dorothy Farrar‐Edwards and Elizabeth S. Burnside and Marc K. Drezner and Amy Taylor and Veena Channamsetty and Wanda Montalvo and Yashoda Sharma and Carmen Chinea and Nancy Jenks and Mine Cicek and Steve N. Thibodeau and Beverly Wilson Holmes and Eric Schlueter and Ever Collier and Joyce Winkler and John P. Corcoran and Nick D’Addezio and Martha L. Daviglus and Robert A. Winn and Consuelo Wilkins and Dan M. Roden and Dan M. Roden and Joshua C. Denny and Kim F. Doheny and Debbie A. Nickerson and Evan E. Eichler and Gail Pairitz Jarvik and Gretchen Funk and Anthony Philippakis and Heidi L. Rehm and Niall J. Lennon and Sekar Kathiresan and Stacey Gabriel and Richard A. Gibbs and Edgar M. Gil Rico and David Glazer and Joannie Grand and Philip Greenland and Paul Harris and Elizabeth A. Shenkman and William R. Hogan and Priscilla E Igho-Pemu and Cliff Pollan and Milena Jorge and Sally Okun and Elizabeth W. Karlson and Jordan W. Smoller and Shawn N. Murphy and Margaret Elizabeth Ross and Rainu Kaushal and Eboni C. Winford and Febe Wallace and Parinda Khatri and Vik Kheterpal and AKINLOLU O. OJO and Francisco Moreno and Irving Louis Kron and Rachele S. Peterson and Usha Menon and Patricia Watkins Lattimore and Noga Leviner and Juno Obedin‐Maliver and Mitchell R. Lunn and Lynda Malik-Gagnon and Lara M. Mangravite and Adria Marallo and Oscar C. Marroquin and Shyam Visweswaran and Steven E. Reís and Gailen D. Marshall and Patrick McGovern and Deb Mignucci and John Moore and Fatima A. Munoz and Gregory Talavera and George T. O’Connor and Christopher J. O’Donnell and Lucila Ohno-machado A and Greg Orr and Fornessa T. Randal and Andreas A. Theodorou and Eric M. Reiman and Mercedita Roxas-Murray and Louisa A. Stark and Ronnie Tepp and Alicia Yiran Zhou and Scott Topper and Rhonda K. Trousdale and Philip S. Tsao and Lisa Weidman and Scott T. Weiss and David Wellis and Jeffrey Whittle and Amanda Wilson and Stephan L. Zuchner and Michael E. Zwick},
journal = {Patterns},
year = {2022},
volume = {3},
number = {8},
pages = {100570},
doi = {10.1016/j.patter.2022.100570},
url = {https://doi.org/10.1016/j.patter.2022.100570}
}TY - JOUR AU - Ramirez, Andrea H. AU - Sulieman, Lina Mahmoud AU - Schlueter, David J. AU - Halvorson, Alese E. AU - Qian, Jun AU - Ratsimbazafy, Francis AU - Loperena, Roxana AU - Mayo, Kelsey AU - Basford, Melissa AU - Deflaux, Nicole A. AU - Muthuraman, Karthik AU - Natarajan, Karthik AU - Kho, Abel AU - Xu, Hua AU - Wilkins, Consuelo Hopkins AU - Anton‐Culver, Hoda AU - Boerwinkle, Eric AU - Cicek, Mine S. AU - Clark, Cheryl R. AU - Cohn, Elizabeth AU - Ohno-Machado, Lucila AU - Schully, Sheri Dixon AU - Ahmedani, Brian Kenneth AU - Argos, Maria AU - Cronin, Robert Michael AU - O’Donnell, Christopher J. AU - Fouad, Mona N. AU - Goldstein, David B. AU - Greenland, Philip AU - Hebbring, Scott Joseph AU - Karlson, Elizabeth W. AU - Khatri, Parinda AU - Korf, Bruce AU - Smoller, Jordan W. AU - Sodeke, Stephen Olufemi AU - WILBANKS, JOHN T. AU - Hentges, Justin AU - Mockrin, Stephen C. AU - Lunt, Chris AU - Devaney, Stephanie A. AU - Gebo, Kelly A. AU - Denny, Joshua C. AU - Carroll, Robert J. AU - Glazer, David AU - Harris, Paul A. AU - Hripcsak, George M. AU - Philippakis, Anthony AU - Roden, Dan M. AU - Roden, Dan M. AU - Ahmedani, Brian Kenneth AU - Johnson, Christine D. Cole AU - Ahsan, Habib AU - Antoine‐LaVigne, Donna AU - Singleton, Glendora AU - Anton-Culver, Hoda AU - Topol, Eric J. AU - Baca-Motes, Katie AU - Steinhubl, Steven R. AU - Wade, James C. AU - Begale, Mark J. AU - Jain, Praduman AU - Sutherland, Scott AU - Lewis, Beth AU - Korf, Bruce R. AU - Behringer, Melissa AU - Gharavi, Ali G. AU - Goldstein, David B. AU - Hripcsak, George M. AU - Bier, Louise AU - Boerwinkle, Eric AU - Brilliant, Murray H. AU - Murali, Narayana S. AU - Hebbring, Scott Joseph AU - Farrar‐Edwards, Dorothy AU - Burnside, Elizabeth S. AU - Drezner, Marc K. AU - Taylor, Amy AU - Channamsetty, Veena AU - Montalvo, Wanda AU - Sharma, Yashoda AU - Chinea, Carmen AU - Jenks, Nancy AU - Cicek, Mine AU - Thibodeau, Steve N. AU - Holmes, Beverly Wilson AU - Schlueter, Eric AU - Collier, Ever AU - Winkler, Joyce AU - Corcoran, John P. AU - D’Addezio, Nick AU - Daviglus, Martha L. AU - Winn, Robert A. AU - Wilkins, Consuelo AU - Roden, Dan M. AU - Roden, Dan M. AU - Denny, Joshua C. AU - Doheny, Kim F. AU - Nickerson, Debbie A. AU - Eichler, Evan E. AU - Jarvik, Gail Pairitz AU - Funk, Gretchen AU - Philippakis, Anthony AU - Rehm, Heidi L. AU - Lennon, Niall J. AU - Kathiresan, Sekar AU - Gabriel, Stacey AU - Gibbs, Richard A. AU - Rico, Edgar M. Gil AU - Glazer, David AU - Grand, Joannie AU - Greenland, Philip AU - Harris, Paul AU - Shenkman, Elizabeth A. AU - Hogan, William R. AU - Igho-Pemu, Priscilla E AU - Pollan, Cliff AU - Jorge, Milena AU - Okun, Sally AU - Karlson, Elizabeth W. AU - Smoller, Jordan W. AU - Murphy, Shawn N. AU - Ross, Margaret Elizabeth AU - Kaushal, Rainu AU - Winford, Eboni C. AU - Wallace, Febe AU - Khatri, Parinda AU - Kheterpal, Vik AU - OJO, AKINLOLU O. AU - Moreno, Francisco AU - Kron, Irving Louis AU - Peterson, Rachele S. AU - Menon, Usha AU - Lattimore, Patricia Watkins AU - Leviner, Noga AU - Obedin‐Maliver, Juno AU - Lunn, Mitchell R. AU - Malik-Gagnon, Lynda AU - Mangravite, Lara M. AU - Marallo, Adria AU - Marroquin, Oscar C. AU - Visweswaran, Shyam AU - Reís, Steven E. AU - Marshall, Gailen D. AU - McGovern, Patrick AU - Mignucci, Deb AU - Moore, John AU - Munoz, Fatima A. AU - Talavera, Gregory AU - O’Connor, George T. AU - O’Donnell, Christopher J. AU - A, Lucila Ohno-machado AU - Orr, Greg AU - Randal, Fornessa T. AU - Theodorou, Andreas A. AU - Reiman, Eric M. AU - Roxas-Murray, Mercedita AU - Stark, Louisa A. AU - Tepp, Ronnie AU - Zhou, Alicia Yiran AU - Topper, Scott AU - Trousdale, Rhonda K. AU - Tsao, Philip S. AU - Weidman, Lisa AU - Weiss, Scott T. AU - Wellis, David AU - Whittle, Jeffrey AU - Wilson, Amanda AU - Zuchner, Stephan L. AU - Zwick, Michael E. TI - The All of Us Research Program: Data quality, utility, and diversity JO - Patterns VL - 3 IS - 8 SP - 100570 PY - 2022 DA - 2022/08/01 DO - 10.1016/j.patter.2022.100570 UR - https://doi.org/10.1016/j.patter.2022.100570 ER -
Add Find Research to Claude or ChatGPT and ask in plain language. The assistant reads this record, finds the papers around it and cites only what it actually found:
Setup takes about a minute: add the connector, then start the free trial.
Record from OpenAlex; open-access location from Unpaywall and the indexes. Find Research links only to legal copies.