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Mark Stasiewicz, Tomasz M. M Karpiński
Despite decades of research, cancer continues to be a major global health concern. In recent years, the role played by microorganisms in the development and progression of cancer has come under increased scrutiny. The aim of the present review is to highlight the main associations between members of the human oral microbiota and various cancers. The PubMed database was searched for available literature to outline the current state of understanding regarding the role of the oral microbiota and a variety of human cancers. Oral squamous cell carcinoma (OSCC) is associated with carriage of a number of oral bacteria (e.g., Porphyromonas gingivalis, Fusobacterium nucleatum, Streptococcus sp.), certain viruses (e.g., human papilloma virus, human herpes virus 8, herpes simplex virus 1 and Epstein-Barr virus) and yeast (Candida albicans). Moreover, members of the oral microbiota are associated with cancers of the esophagus, stomach, pancreas, colon/rectum and lung. Furthermore, the present review outlines a number of the carcinogenic mechanisms underlying the presented microbial associations with cancer. Such information may one day help clinicians to diagnose neoplastic diseases at earlier stages and prescribe treatments that take into account the possible microbial nature of carcinogenesis.
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Stasiewicz, M., & Karpiński, T. M. M. (2021). The oral microbiota and its role in carcinogenesis. Seminars in Cancer Biology, 86(Pt 3), 633–642. https://doi.org/10.1016/j.semcancer.2021.11.002
Stasiewicz, Mark, and Tomasz M. M Karpiński. "The oral microbiota and its role in carcinogenesis." Seminars in Cancer Biology, vol. 86, no. Pt 3, 2021, pp. 633–642, https://doi.org/10.1016/j.semcancer.2021.11.002.
Stasiewicz, Mark, and Tomasz M. M Karpiński. "The oral microbiota and its role in carcinogenesis." Seminars in Cancer Biology 86, no. Pt 3 (2021): 633–642. https://doi.org/10.1016/j.semcancer.2021.11.002.
Stasiewicz M., Karpiński T. M. M. The oral microbiota and its role in carcinogenesis // Seminars in Cancer Biology. — 2021. — Vol. 86, № Pt 3. — P. 633–642. — URL: https://doi.org/10.1016/j.semcancer.2021.11.002
@article{stasiewicz2021oral,
title = {{The oral microbiota and its role in carcinogenesis}},
author = {Mark Stasiewicz and Tomasz M. M Karpiński},
journal = {Seminars in Cancer Biology},
year = {2021},
volume = {86},
number = {Pt 3},
pages = {633--642},
doi = {10.1016/j.semcancer.2021.11.002},
url = {https://doi.org/10.1016/j.semcancer.2021.11.002}
}TY - JOUR AU - Stasiewicz, Mark AU - Karpiński, Tomasz M. M TI - The oral microbiota and its role in carcinogenesis JO - Seminars in Cancer Biology VL - 86 IS - Pt 3 SP - 633 EP - 642 PY - 2021 DA - 2021/11/04 DO - 10.1016/j.semcancer.2021.11.002 UR - https://doi.org/10.1016/j.semcancer.2021.11.002 ER -
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