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Yue Xi, Pengfei Xu
As the third most common malignancy and the second most deadly cancer, colorectal cancer (CRC) induces estimated 1.9 million incidence cases and 0.9 million deaths worldwide in 2020. The incidence of CRC is higher in highly developed countries, and it is increasing in middle- and low-income countries due to westernization. Moreover, a rising incidence of early-onset CRC is also emerging. The large number of CRC cases poses a growing global public health challenge. Raising awareness of CRC is important to promote healthy lifestyle choices, novel strategies for CRC management, and implementation of global screening programs, which are critical to reducing CRC morbidity and mortality in the future. CRC is a heterogeneous disease, and its subtype affiliation influences prognosis and therapeutic response. An accurate CRC subtype classification system is of great significance for basic research and clinical outcome. Here, we present the global epidemiology of CRC in 2020 and projections for 2040, review the major CRC subtypes to better understand CRC molecular basis, and summarize current risk factors, prevention, and screening strategies for CRC.
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Xi, Y., & Xu, P. (2021). Global colorectal cancer burden in 2020 and projections to 2040. Translational Oncology, 14(10), 101174. https://doi.org/10.1016/j.tranon.2021.101174
Xi, Yue, and Pengfei Xu. "Global colorectal cancer burden in 2020 and projections to 2040." Translational Oncology, vol. 14, no. 10, 2021, pp. 101174, https://doi.org/10.1016/j.tranon.2021.101174.
Xi, Yue, and Pengfei Xu. "Global colorectal cancer burden in 2020 and projections to 2040." Translational Oncology 14, no. 10 (2021): 101174. https://doi.org/10.1016/j.tranon.2021.101174.
Xi Y., Xu P. Global colorectal cancer burden in 2020 and projections to 2040 // Translational Oncology. — 2021. — Vol. 14, № 10. — P. 101174. — URL: https://doi.org/10.1016/j.tranon.2021.101174
@article{xi2021global,
title = {{Global colorectal cancer burden in 2020 and projections to 2040}},
author = {Yue Xi and Pengfei Xu},
journal = {Translational Oncology},
year = {2021},
volume = {14},
number = {10},
pages = {101174},
doi = {10.1016/j.tranon.2021.101174},
url = {https://doi.org/10.1016/j.tranon.2021.101174}
}TY - JOUR AU - Xi, Yue AU - Xu, Pengfei TI - Global colorectal cancer burden in 2020 and projections to 2040 JO - Translational Oncology VL - 14 IS - 10 SP - 101174 PY - 2021 DA - 2021/07/06 DO - 10.1016/j.tranon.2021.101174 UR - https://doi.org/10.1016/j.tranon.2021.101174 ER -
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