One connector, four scholarly indexes, real DOIs and legal free PDFs. Works in Claude and ChatGPT.
Paste it into Claude or ChatGPT as a custom connector. 3-day free trial.
Liyun Chen, Junxia Min, Fudi Wang
As an essential micronutrient, copper is required for a wide range of physiological processes in virtually all cell types. Because the accumulation of intracellular copper can induce oxidative stress and perturbing cellular function, copper homeostasis is tightly regulated. Recent studies identified a novel copper-dependent form of cell death called cuproptosis, which is distinct from all other known pathways underlying cell death. Cuproptosis occurs via copper binding to lipoylated enzymes in the tricarboxylic acid (TCA) cycle, which leads to subsequent protein aggregation, proteotoxic stress, and ultimately cell death. Here, we summarize our current knowledge regarding copper metabolism, copper-related disease, the characteristics of cuproptosis, and the mechanisms that regulate cuproptosis. In addition, we discuss the implications of cuproptosis in the pathogenesis of various disease conditions, including Wilson's disease, neurodegenerative diseases, and cancer, and we discuss the therapeutic potential of targeting cuproptosis.
Formatted from the source metadata, not typed by hand. For a whole reference list, use the citation generator or ask your assistant through Find Research.
Chen, L., Min, J., & Wang, F. (2022). Copper homeostasis and cuproptosis in health and disease. Signal Transduction and Targeted Therapy, 7(1), 378. https://doi.org/10.1038/s41392-022-01229-y
Chen, Liyun, et al. "Copper homeostasis and cuproptosis in health and disease." Signal Transduction and Targeted Therapy, vol. 7, no. 1, 2022, pp. 378, https://doi.org/10.1038/s41392-022-01229-y.
Chen, Liyun, Junxia Min, and Fudi Wang. "Copper homeostasis and cuproptosis in health and disease." Signal Transduction and Targeted Therapy 7, no. 1 (2022): 378. https://doi.org/10.1038/s41392-022-01229-y.
Chen L., Min J., Wang F. Copper homeostasis and cuproptosis in health and disease // Signal Transduction and Targeted Therapy. — 2022. — Vol. 7, № 1. — P. 378. — URL: https://doi.org/10.1038/s41392-022-01229-y
@article{chen2022copper,
title = {{Copper homeostasis and cuproptosis in health and disease}},
author = {Liyun Chen and Junxia Min and Fudi Wang},
journal = {Signal Transduction and Targeted Therapy},
year = {2022},
volume = {7},
number = {1},
pages = {378},
doi = {10.1038/s41392-022-01229-y},
url = {https://doi.org/10.1038/s41392-022-01229-y}
}TY - JOUR AU - Chen, Liyun AU - Min, Junxia AU - Wang, Fudi TI - Copper homeostasis and cuproptosis in health and disease JO - Signal Transduction and Targeted Therapy VL - 7 IS - 1 SP - 378 PY - 2022 DA - 2022/11/22 DO - 10.1038/s41392-022-01229-y UR - https://doi.org/10.1038/s41392-022-01229-y ER -
Add Find Research to Claude or ChatGPT and ask in plain language. The assistant reads this record, finds the papers around it and cites only what it actually found:
Setup takes about a minute: add the connector, then start the free trial.
Record from OpenAlex; open-access location from Unpaywall and the indexes. Find Research links only to legal copies.