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Xue Zhou, Youdong Chen, Lian Cui, Yuling Shi, Chunyuan Guo
Psoriasis is a complex long-lasting inflammatory skin disease with high prevalence and associated comorbidity. It is characterized by epidermal hyperplasia and dermal infiltration of immune cells. Here, we review the role of keratinocytes in the pathogenesis of psoriasis, focusing on factors relevant to genetics, cytokines and receptors, metabolism, cell signaling, transcription factors, non-coding RNAs, antimicrobial peptides, and proteins with other different functions. The critical role of keratinocytes in initiating and maintaining the inflammatory state suggests the great significance of targeting keratinocytes for the treatment of psoriasis.
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Zhou, X., Chen, Y., Cui, L., Shi, Y., & Guo, C. (2022). Advances in the pathogenesis of psoriasis: from keratinocyte perspective. Cell Death and Disease, 13(1), 81. https://doi.org/10.1038/s41419-022-04523-3
Zhou, Xue, et al. "Advances in the pathogenesis of psoriasis: from keratinocyte perspective." Cell Death and Disease, vol. 13, no. 1, 2022, pp. 81, https://doi.org/10.1038/s41419-022-04523-3.
Zhou, Xue, Youdong Chen, Lian Cui, Yuling Shi, and Chunyuan Guo. "Advances in the pathogenesis of psoriasis: from keratinocyte perspective." Cell Death and Disease 13, no. 1 (2022): 81. https://doi.org/10.1038/s41419-022-04523-3.
Zhou X., Chen Y., Cui L. [и др.] Advances in the pathogenesis of psoriasis: from keratinocyte perspective // Cell Death and Disease. — 2022. — Vol. 13, № 1. — P. 81. — URL: https://doi.org/10.1038/s41419-022-04523-3
@article{zhou2022advances,
title = {{Advances in the pathogenesis of psoriasis: from keratinocyte perspective}},
author = {Xue Zhou and Youdong Chen and Lian Cui and Yuling Shi and Chunyuan Guo},
journal = {Cell Death and Disease},
year = {2022},
volume = {13},
number = {1},
pages = {81},
doi = {10.1038/s41419-022-04523-3},
url = {https://doi.org/10.1038/s41419-022-04523-3}
}TY - JOUR AU - Zhou, Xue AU - Chen, Youdong AU - Cui, Lian AU - Shi, Yuling AU - Guo, Chunyuan TI - Advances in the pathogenesis of psoriasis: from keratinocyte perspective JO - Cell Death and Disease VL - 13 IS - 1 SP - 81 PY - 2022 DA - 2022/01/24 DO - 10.1038/s41419-022-04523-3 UR - https://doi.org/10.1038/s41419-022-04523-3 ER -
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