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Xinyue Chen, Qi Cai, Ruikai Liang, Deju Zhang, Xiao Liu, Meiying Zhang, Yan Xiong, Minxuan Xu, Qi Liu, Pengyang Li, Peng Yu, Ao Shi
Copper is a vital mineral, and an optimal amount of copper is required to support normal physiologic processes in various systems, including the cardiovascular system. Over the past few decades, copper-induced cell death, named cuproptosis, has become increasingly recognized as an important process mediating the pathogenesis and progression of cardiovascular disease (CVD), including atherosclerosis, stroke, ischemia-reperfusion injury, and heart failure. Therefore, an in-depth understanding of the regulatory mechanisms of cuproptosis in CVD may be useful for improving CVD management. Here, we review the relationship between copper homeostasis and cuproptosis-related pathways in CVD, as well as therapeutic strategies addressing copper-induced cell death in CVD.
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Chen, X., Cai, Q., Liang, R., Zhang, D., Liu, X., Zhang, M., Xiong, Y., Xu, M., Liu, Q., Li, P., Yu, P., & Shi, A. (2023). Copper homeostasis and copper-induced cell death in the pathogenesis of cardiovascular disease and therapeutic strategies. Cell Death and Disease, 14(2), 105. https://doi.org/10.1038/s41419-023-05639-w
Chen, Xinyue, et al. "Copper homeostasis and copper-induced cell death in the pathogenesis of cardiovascular disease and therapeutic strategies." Cell Death and Disease, vol. 14, no. 2, 2023, pp. 105, https://doi.org/10.1038/s41419-023-05639-w.
Chen, Xinyue, Qi Cai, Ruikai Liang, Deju Zhang, Xiao Liu, Meiying Zhang, Yan Xiong, et al. "Copper homeostasis and copper-induced cell death in the pathogenesis of cardiovascular disease and therapeutic strategies." Cell Death and Disease 14, no. 2 (2023): 105. https://doi.org/10.1038/s41419-023-05639-w.
Chen X., Cai Q., Liang R. [и др.] Copper homeostasis and copper-induced cell death in the pathogenesis of cardiovascular disease and therapeutic strategies // Cell Death and Disease. — 2023. — Vol. 14, № 2. — P. 105. — URL: https://doi.org/10.1038/s41419-023-05639-w
@article{chen2023copper,
title = {{Copper homeostasis and copper-induced cell death in the pathogenesis of cardiovascular disease and therapeutic strategies}},
author = {Xinyue Chen and Qi Cai and Ruikai Liang and Deju Zhang and Xiao Liu and Meiying Zhang and Yan Xiong and Minxuan Xu and Qi Liu and Pengyang Li and Peng Yu and Ao Shi},
journal = {Cell Death and Disease},
year = {2023},
volume = {14},
number = {2},
pages = {105},
doi = {10.1038/s41419-023-05639-w},
url = {https://doi.org/10.1038/s41419-023-05639-w}
}TY - JOUR AU - Chen, Xinyue AU - Cai, Qi AU - Liang, Ruikai AU - Zhang, Deju AU - Liu, Xiao AU - Zhang, Meiying AU - Xiong, Yan AU - Xu, Minxuan AU - Liu, Qi AU - Li, Pengyang AU - Yu, Peng AU - Shi, Ao TI - Copper homeostasis and copper-induced cell death in the pathogenesis of cardiovascular disease and therapeutic strategies JO - Cell Death and Disease VL - 14 IS - 2 SP - 105 PY - 2023 DA - 2023/02/11 DO - 10.1038/s41419-023-05639-w UR - https://doi.org/10.1038/s41419-023-05639-w ER -
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