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Damien Bertheloot, Eicke Latz, Bernardo S. Franklin
Cell death is a fundamental physiological process in all living organisms. Its roles extend from embryonic development, organ maintenance, and aging to the coordination of immune responses and autoimmunity. In recent years, our understanding of the mechanisms orchestrating cellular death and its consequences on immunity and homeostasis has increased substantially. Different modalities of what has become known as 'programmed cell death' have been described, and some key players in these processes have been identified. We have learned more about the intricacies that fine tune the activity of common players and ultimately shape the different types of cell death. These studies have highlighted the complex mechanisms tipping the balance between different cell fates. Here, we summarize the latest discoveries in the three most well understood modalities of cell death, namely, apoptosis, necroptosis, and pyroptosis, highlighting common and unique pathways and their effect on the surrounding cells and the organism as a whole.
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Bertheloot, D., Latz, E., & Franklin, B. S. (2021). Necroptosis, pyroptosis and apoptosis: an intricate game of cell death. Cellular and Molecular Immunology, 18(5), 1106–1121. https://doi.org/10.1038/s41423-020-00630-3
Bertheloot, Damien, et al. "Necroptosis, pyroptosis and apoptosis: an intricate game of cell death." Cellular and Molecular Immunology, vol. 18, no. 5, 2021, pp. 1106–1121, https://doi.org/10.1038/s41423-020-00630-3.
Bertheloot, Damien, Eicke Latz, and Bernardo S. Franklin. "Necroptosis, pyroptosis and apoptosis: an intricate game of cell death." Cellular and Molecular Immunology 18, no. 5 (2021): 1106–1121. https://doi.org/10.1038/s41423-020-00630-3.
Bertheloot D., Latz E., Franklin B. S. Necroptosis, pyroptosis and apoptosis: an intricate game of cell death // Cellular and Molecular Immunology. — 2021. — Vol. 18, № 5. — P. 1106–1121. — URL: https://doi.org/10.1038/s41423-020-00630-3
@article{bertheloot2021necroptosis,
title = {{Necroptosis, pyroptosis and apoptosis: an intricate game of cell death}},
author = {Damien Bertheloot and Eicke Latz and Bernardo S. Franklin},
journal = {Cellular and Molecular Immunology},
year = {2021},
volume = {18},
number = {5},
pages = {1106--1121},
doi = {10.1038/s41423-020-00630-3},
url = {https://doi.org/10.1038/s41423-020-00630-3}
}TY - JOUR AU - Bertheloot, Damien AU - Latz, Eicke AU - Franklin, Bernardo S. TI - Necroptosis, pyroptosis and apoptosis: an intricate game of cell death JO - Cellular and Molecular Immunology VL - 18 IS - 5 SP - 1106 EP - 1121 PY - 2021 DA - 2021/03/30 DO - 10.1038/s41423-020-00630-3 UR - https://doi.org/10.1038/s41423-020-00630-3 ER -
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