- Published
- 2021-04-01
- Venue
- Nature Methods, vol. 18, no. 4, pp. 366-368
- Cited by
- 5,063
- Open access
- Yes, hybrid
- DOI
- 10.1038/s41592-021-01101-x
- PubMed
- 33828273
Abstract
We are at the beginning of a genomic revolution in which all known species are planned to be sequenced. Accessing such data for comparative analyses is crucial in this new age of data-driven biology. Here, we introduce an improved version of DIAMOND that greatly exceeds previous search performances and harnesses supercomputing to perform tree-of-life scale protein alignments in hours, while matching the sensitivity of the gold standard BLASTP.
Cite this paper
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- APA 7
Buchfink, B., Reuter, K., & Drost, H. (2021). Sensitive protein alignments at tree-of-life scale using DIAMOND. Nature Methods, 18(4), 366–368. https://doi.org/10.1038/s41592-021-01101-x
- MLA 9
Buchfink, Benjamin, et al. "Sensitive protein alignments at tree-of-life scale using DIAMOND." Nature Methods, vol. 18, no. 4, 2021, pp. 366–368, https://doi.org/10.1038/s41592-021-01101-x.
- Chicago
Buchfink, Benjamin, Klaus Reuter, and Hajk‐Georg Drost. "Sensitive protein alignments at tree-of-life scale using DIAMOND." Nature Methods 18, no. 4 (2021): 366–368. https://doi.org/10.1038/s41592-021-01101-x.
- GOST
Buchfink B., Reuter K., Drost H. Sensitive protein alignments at tree-of-life scale using DIAMOND // Nature Methods. — 2021. — Vol. 18, № 4. — P. 366–368. — URL: https://doi.org/10.1038/s41592-021-01101-x
- BibTeX
@article{buchfink2021sensitive, title = {{Sensitive protein alignments at tree-of-life scale using DIAMOND}}, author = {Benjamin Buchfink and Klaus Reuter and Hajk‐Georg Drost}, journal = {Nature Methods}, year = {2021}, volume = {18}, number = {4}, pages = {366--368}, doi = {10.1038/s41592-021-01101-x}, url = {https://doi.org/10.1038/s41592-021-01101-x} }- RIS
TY - JOUR AU - Buchfink, Benjamin AU - Reuter, Klaus AU - Drost, Hajk‐Georg TI - Sensitive protein alignments at tree-of-life scale using DIAMOND JO - Nature Methods VL - 18 IS - 4 SP - 366 EP - 368 PY - 2021 DA - 2021/04/01 DO - 10.1038/s41592-021-01101-x UR - https://doi.org/10.1038/s41592-021-01101-x ER -