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Yifang Zhao, Heng Zeng, Xiaowei Zhu, Weigang Lu, Dan Li
Biosensing is of vital importance for advancing public health through monitoring abnormalities in biological systems, which may be potentially associated with certain body dysfunctions. A wide range of luminescent materials have been actively pursued in the fabrication of biosensing platforms, particularly ones that can function in complex biological fluids with high selectivity and sensitivity. Recently, metal-organic frameworks (MOFs) have experienced rapid growth due to their tunable structures, large surface area, and being prone to surface engineering, etc. These virtues endow MOF materials with immense feasibility in the target-oriented construction of sensing platforms for specific applications. In this review, we extrapolated six sensing mechanisms for MOF-based photoluminescent biosensing platforms, including photoelectron transfer (PET), resonance energy transfer (RET), competition absorption (CA), structural transformation (ST), chemical conversion (CC), and quencher detachment (QD). Accordingly, recent progress of MOF-based materials in photoluminescence sensing of biomolecules, biomarkers, drugs, and toxins was highlighted. The objective of this review is to provide readers with an extensive overview of the design and synthesis of MOF materials for photoluminescence biosensing. The challenges and outlook are briefly discussed at the end.
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Zhao, Y., Zeng, H., Zhu, X., Lu, W., & Li, D. (2021). Metal–organic frameworks as photoluminescent biosensing platforms: mechanisms and applications. Chemical Society Reviews, 50(7), 4484–4513. https://doi.org/10.1039/d0cs00955e
Zhao, Yifang, et al. "Metal–organic frameworks as photoluminescent biosensing platforms: mechanisms and applications." Chemical Society Reviews, vol. 50, no. 7, 2021, pp. 4484–4513, https://doi.org/10.1039/d0cs00955e.
Zhao, Yifang, Heng Zeng, Xiaowei Zhu, Weigang Lu, and Dan Li. "Metal–organic frameworks as photoluminescent biosensing platforms: mechanisms and applications." Chemical Society Reviews 50, no. 7 (2021): 4484–4513. https://doi.org/10.1039/d0cs00955e.
Zhao Y., Zeng H., Zhu X. [и др.] Metal–organic frameworks as photoluminescent biosensing platforms: mechanisms and applications // Chemical Society Reviews. — 2021. — Vol. 50, № 7. — P. 4484–4513. — URL: https://doi.org/10.1039/d0cs00955e
@article{zhao2021metalorganic,
title = {{Metal–organic frameworks as photoluminescent biosensing platforms: mechanisms and applications}},
author = {Yifang Zhao and Heng Zeng and Xiaowei Zhu and Weigang Lu and Dan Li},
journal = {Chemical Society Reviews},
year = {2021},
volume = {50},
number = {7},
pages = {4484--4513},
doi = {10.1039/d0cs00955e},
url = {https://doi.org/10.1039/d0cs00955e}
}TY - JOUR AU - Zhao, Yifang AU - Zeng, Heng AU - Zhu, Xiaowei AU - Lu, Weigang AU - Li, Dan TI - Metal–organic frameworks as photoluminescent biosensing platforms: mechanisms and applications JO - Chemical Society Reviews VL - 50 IS - 7 SP - 4484 EP - 4513 PY - 2021 DA - 2021/01/01 DO - 10.1039/d0cs00955e UR - https://doi.org/10.1039/d0cs00955e ER -
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