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Xue Tian, Lloyd C. Murfin, Luling Wu, Simon E. Lewis, Tony D. James
Small-molecule based fluorescent probes are increasingly important for the detection and imaging of biological signaling molecules due to their simplicity, high selectivity and sensitivity, whilst being non-invasive, and suitable for real-time analysis of living systems. With this perspective we highlight sensing mechanisms including Förster resonance energy transfer (FRET), intramolecular charge transfer (ICT), photoinduced electron transfer (PeT), excited state intramolecular proton transfer (ESIPT), aggregation induced emission (AIE) and multiple modality fluorescence approaches including dual/triple sensing mechanisms (DSM or TSM). Throughout the perspective we highlight the remaining challenges and suggest potential directions for development towards improved small-molecule fluorescent probes suitable for biosensing.
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Tian, X., Murfin, L. C., Wu, L., Lewis, S. E., & James, T. D. (2021). Fluorescent small organic probes for biosensing. Chemical Science, 12(10), 3406–3426. https://doi.org/10.1039/d0sc06928k
Tian, Xue, et al. "Fluorescent small organic probes for biosensing." Chemical Science, vol. 12, no. 10, 2021, pp. 3406–3426, https://doi.org/10.1039/d0sc06928k.
Tian, Xue, Lloyd C. Murfin, Luling Wu, Simon E. Lewis, and Tony D. James. "Fluorescent small organic probes for biosensing." Chemical Science 12, no. 10 (2021): 3406–3426. https://doi.org/10.1039/d0sc06928k.
Tian X., Murfin L. C., Wu L. [и др.] Fluorescent small organic probes for biosensing // Chemical Science. — 2021. — Vol. 12, № 10. — P. 3406–3426. — URL: https://doi.org/10.1039/d0sc06928k
@article{tian2021fluorescent,
title = {{Fluorescent small organic probes for biosensing}},
author = {Xue Tian and Lloyd C. Murfin and Luling Wu and Simon E. Lewis and Tony D. James},
journal = {Chemical Science},
year = {2021},
volume = {12},
number = {10},
pages = {3406--3426},
doi = {10.1039/d0sc06928k},
url = {https://doi.org/10.1039/d0sc06928k}
}TY - JOUR AU - Tian, Xue AU - Murfin, Lloyd C. AU - Wu, Luling AU - Lewis, Simon E. AU - James, Tony D. TI - Fluorescent small organic probes for biosensing JO - Chemical Science VL - 12 IS - 10 SP - 3406 EP - 3426 PY - 2021 DA - 2021/01/01 DO - 10.1039/d0sc06928k UR - https://doi.org/10.1039/d0sc06928k ER -
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