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Carlos P. Cantalapiedra, Ana Hernández-Plaza, Ivica Letunić, Peer Bork B, Jaime Huerta‐Cepas
Even though automated functional annotation of genes represents a fundamental step in most genomic and metagenomic workflows, it remains challenging at large scales. Here, we describe a major upgrade to eggNOG-mapper, a tool for functional annotation based on precomputed orthology assignments, now optimized for vast (meta)genomic data sets. Improvements in version 2 include a full update of both the genomes and functional databases to those from eggNOG v5, as well as several efficiency enhancements and new features. Most notably, eggNOG-mapper v2 now allows for: 1) de novo gene prediction from raw contigs, 2) built-in pairwise orthology prediction, 3) fast protein domain discovery, and 4) automated GFF decoration. eggNOG-mapper v2 is available as a standalone tool or as an online service at http://eggnog-mapper.embl.de.
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Cantalapiedra, C. P., Hernández-Plaza, A., Letunić, I., B, P. B., & Huerta‐Cepas, J. (2021). eggNOG-mapper v2: Functional Annotation, Orthology Assignments, and Domain Prediction at the Metagenomic Scale. Molecular Biology and Evolution, 38(12), 5825–5829. https://doi.org/10.1093/molbev/msab293
Cantalapiedra, Carlos P., et al. "eggNOG-mapper v2: Functional Annotation, Orthology Assignments, and Domain Prediction at the Metagenomic Scale." Molecular Biology and Evolution, vol. 38, no. 12, 2021, pp. 5825–5829, https://doi.org/10.1093/molbev/msab293.
Cantalapiedra, Carlos P., Ana Hernández-Plaza, Ivica Letunić, Peer Bork B, and Jaime Huerta‐Cepas. "eggNOG-mapper v2: Functional Annotation, Orthology Assignments, and Domain Prediction at the Metagenomic Scale." Molecular Biology and Evolution 38, no. 12 (2021): 5825–5829. https://doi.org/10.1093/molbev/msab293.
Cantalapiedra C. P., Hernández-Plaza A., Letunić I. [и др.] eggNOG-mapper v2: Functional Annotation, Orthology Assignments, and Domain Prediction at the Metagenomic Scale // Molecular Biology and Evolution. — 2021. — Vol. 38, № 12. — P. 5825–5829. — URL: https://doi.org/10.1093/molbev/msab293
@article{cantalapiedra2021eggnogmapper,
title = {{eggNOG-mapper v2: Functional Annotation, Orthology Assignments, and Domain Prediction at the Metagenomic Scale}},
author = {Carlos P. Cantalapiedra and Ana Hernández-Plaza and Ivica Letunić and Peer Bork B and Jaime Huerta‐Cepas},
journal = {Molecular Biology and Evolution},
year = {2021},
volume = {38},
number = {12},
pages = {5825--5829},
doi = {10.1093/molbev/msab293},
url = {https://doi.org/10.1093/molbev/msab293}
}TY - JOUR AU - Cantalapiedra, Carlos P. AU - Hernández-Plaza, Ana AU - Letunić, Ivica AU - B, Peer Bork AU - Huerta‐Cepas, Jaime TI - eggNOG-mapper v2: Functional Annotation, Orthology Assignments, and Domain Prediction at the Metagenomic Scale JO - Molecular Biology and Evolution VL - 38 IS - 12 SP - 5825 EP - 5829 PY - 2021 DA - 2021/09/30 DO - 10.1093/molbev/msab293 UR - https://doi.org/10.1093/molbev/msab293 ER -
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