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Élodie Drula, Marie-Line Garron, Suzan Dogan, Vincent Lombard, Bernard Henrissat, Nicolas Terrapon
Thirty years have elapsed since the emergence of the classification of carbohydrate-active enzymes in sequence-based families that became the CAZy database over 20 years ago, freely available for browsing and download at www.cazy.org. In the era of large scale sequencing and high-throughput Biology, it is important to examine the position of this specialist database that is deeply rooted in human curation. The three primary tasks of the CAZy curators are (i) to maintain and update the family classification of this class of enzymes, (ii) to classify sequences newly released by GenBank and the Protein Data Bank and (iii) to capture and present functional information for each family. The CAZy website is updated once a month. Here we briefly summarize the increase in novel families and the annotations conducted during the last 8 years. We present several important changes that facilitate taxonomic navigation, and allow to download the entirety of the annotations. Most importantly we highlight the considerable amount of work that accompanies the analysis and report of biochemical data from the literature.
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Drula, É., Garron, M.-L., Dogan, S., Lombard, V., Henrissat, B., & Terrapon, N. (2021). The carbohydrate-active enzyme database: functions and literature. Nucleic Acids Research, 50(D1), D571–D577. https://doi.org/10.1093/nar/gkab1045
Drula, Élodie, et al. "The carbohydrate-active enzyme database: functions and literature." Nucleic Acids Research, vol. 50, no. D1, 2021, pp. D571–D577, https://doi.org/10.1093/nar/gkab1045.
Drula, Élodie, Marie-Line Garron, Suzan Dogan, Vincent Lombard, Bernard Henrissat, and Nicolas Terrapon. "The carbohydrate-active enzyme database: functions and literature." Nucleic Acids Research 50, no. D1 (2021): D571–D577. https://doi.org/10.1093/nar/gkab1045.
Drula É., Garron M.-L., Dogan S. [и др.] The carbohydrate-active enzyme database: functions and literature // Nucleic Acids Research. — 2021. — Vol. 50, № D1. — P. D571–D577. — URL: https://doi.org/10.1093/nar/gkab1045
@article{drula2021carbohydrateactive,
title = {{The carbohydrate-active enzyme database: functions and literature}},
author = {Élodie Drula and Marie-Line Garron and Suzan Dogan and Vincent Lombard and Bernard Henrissat and Nicolas Terrapon},
journal = {Nucleic Acids Research},
year = {2021},
volume = {50},
number = {D1},
pages = {D571--D577},
doi = {10.1093/nar/gkab1045},
url = {https://doi.org/10.1093/nar/gkab1045}
}TY - JOUR AU - Drula, Élodie AU - Garron, Marie-Line AU - Dogan, Suzan AU - Lombard, Vincent AU - Henrissat, Bernard AU - Terrapon, Nicolas TI - The carbohydrate-active enzyme database: functions and literature JO - Nucleic Acids Research VL - 50 IS - D1 SP - D571 EP - D577 PY - 2021 DA - 2021/10/15 DO - 10.1093/nar/gkab1045 UR - https://doi.org/10.1093/nar/gkab1045 ER -
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