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Kai Blin, Simon Shaw, Hannah E. Augustijn, Zachary L. Reitz, Friederike Biermann, Mohammad M. Alanjary, Artem Fetter, Barbara R. Terlouw, William W. Metcalf, Eric J. N. Helfrich and 3 more
Microorganisms produce small bioactive compounds as part of their secondary or specialised metabolism. Often, such metabolites have antimicrobial, anticancer, antifungal, antiviral or other bio-activities and thus play an important role for applications in medicine and agriculture. In the past decade, genome mining has become a widely-used method to explore, access, and analyse the available biodiversity of these compounds. Since 2011, the 'antibiotics and secondary metabolite analysis shell-antiSMASH' (https://antismash.secondarymetabolites.org/) has supported researchers in their microbial genome mining tasks, both as a free to use web server and as a standalone tool under an OSI-approved open source licence. It is currently the most widely used tool for detecting and characterising biosynthetic gene clusters (BGCs) in archaea, bacteria, and fungi. Here, we present the updated version 7 of antiSMASH. antiSMASH 7 increases the number of supported cluster types from 71 to 81, as well as containing improvements in the areas of chemical structure prediction, enzymatic assembly-line visualisation and gene cluster regulation.
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Blin, K., Shaw, S., Augustijn, H. E., Reitz, Z. L., Biermann, F., Alanjary, M. M., Fetter, A., Terlouw, B. R., Metcalf, W. W., Helfrich, E. J. N., Wezel, G. P. V., Medema, M. H., & Weber, T. (2023). antiSMASH 7.0: new and improved predictions for detection, regulation, chemical structures and visualisation. Nucleic Acids Research, 51(W1), W46–W50. https://doi.org/10.1093/nar/gkad344
Blin, Kai, et al. "antiSMASH 7.0: new and improved predictions for detection, regulation, chemical structures and visualisation." Nucleic Acids Research, vol. 51, no. W1, 2023, pp. W46–W50, https://doi.org/10.1093/nar/gkad344.
Blin, Kai, Simon Shaw, Hannah E. Augustijn, Zachary L. Reitz, Friederike Biermann, Mohammad M. Alanjary, Artem Fetter, et al. "antiSMASH 7.0: new and improved predictions for detection, regulation, chemical structures and visualisation." Nucleic Acids Research 51, no. W1 (2023): W46–W50. https://doi.org/10.1093/nar/gkad344.
Blin K., Shaw S., Augustijn H. E. [и др.] antiSMASH 7.0: new and improved predictions for detection, regulation, chemical structures and visualisation // Nucleic Acids Research. — 2023. — Vol. 51, № W1. — P. W46–W50. — URL: https://doi.org/10.1093/nar/gkad344
@article{blin2023antismash,
title = {{antiSMASH 7.0: new and improved predictions for detection, regulation, chemical structures and visualisation}},
author = {Kai Blin and Simon Shaw and Hannah E. Augustijn and Zachary L. Reitz and Friederike Biermann and Mohammad M. Alanjary and Artem Fetter and Barbara R. Terlouw and William W. Metcalf and Eric J. N. Helfrich and Gilles P. van Wezel and Marnix H. Medema and Tilmann Weber},
journal = {Nucleic Acids Research},
year = {2023},
volume = {51},
number = {W1},
pages = {W46--W50},
doi = {10.1093/nar/gkad344},
url = {https://doi.org/10.1093/nar/gkad344}
}TY - JOUR AU - Blin, Kai AU - Shaw, Simon AU - Augustijn, Hannah E. AU - Reitz, Zachary L. AU - Biermann, Friederike AU - Alanjary, Mohammad M. AU - Fetter, Artem AU - Terlouw, Barbara R. AU - Metcalf, William W. AU - Helfrich, Eric J. N. AU - Wezel, Gilles P. van AU - Medema, Marnix H. AU - Weber, Tilmann TI - antiSMASH 7.0: new and improved predictions for detection, regulation, chemical structures and visualisation JO - Nucleic Acids Research VL - 51 IS - W1 SP - W46 EP - W50 PY - 2023 DA - 2023/05/04 DO - 10.1093/nar/gkad344 UR - https://doi.org/10.1093/nar/gkad344 ER -
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