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Alex G. Bateman, Maria Jesus Martin, Sandra E. Orchard, Michele Magrane, Aduragbemi S. Adesina, Shadab Ahmad, Emily Bowler-Barnett, Hema Bye‐A‐Jee, David C. J. Carpentier, Paul Denny and 89 more
The aim of the UniProt Knowledgebase (UniProtKB; https://www.uniprot.org/) is to provide users with a comprehensive, high-quality and freely accessible set of protein sequences annotated with functional information. In this publication, we describe ongoing changes to our production pipeline to limit the sequences available in UniProtKB to high-quality, non-redundant reference proteomes. We continue to manually curate the scientific literature to add the latest functional data and use machine learning techniques. We also encourage community curation to ensure key publications are not missed. We provide an update on the automatic annotation methods used by UniProtKB to predict information for unreviewed entries describing unstudied proteins. Finally, updates to the UniProt website are described, including a new tab linking protein to genomic information. In recognition of its value to the scientific community, the UniProt database has been awarded Global Core Biodata Resource status.
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Bateman, A. G., Martin, M. J., Orchard, S. E., Magrane, M., Adesina, A. S., Ahmad, S., Bowler-Barnett, E., Bye‐A‐Jee, H., Carpentier, D. C. J., Denny, P., Fan, J., Garmiri, P., Gonzales, L. J. D. C., Hussein, A., Ignatchenko, A., Insana, G., Ishtiaq, R., Joshi, V., Jyothi, D., … Zhang, J. (2024). UniProt: the Universal Protein Knowledgebase in 2025. Nucleic Acids Research, 53(D1), D609–D617. https://doi.org/10.1093/nar/gkae1010
Bateman, Alex G., et al. "UniProt: the Universal Protein Knowledgebase in 2025." Nucleic Acids Research, vol. 53, no. D1, 2024, pp. D609–D617, https://doi.org/10.1093/nar/gkae1010.
Bateman, Alex G., Maria Jesus Martin, Sandra E. Orchard, Michele Magrane, Aduragbemi S. Adesina, Shadab Ahmad, Emily Bowler-Barnett, et al. "UniProt: the Universal Protein Knowledgebase in 2025." Nucleic Acids Research 53, no. D1 (2024): D609–D617. https://doi.org/10.1093/nar/gkae1010.
Bateman A. G., Martin M. J., Orchard S. E. [и др.] UniProt: the Universal Protein Knowledgebase in 2025 // Nucleic Acids Research. — 2024. — Vol. 53, № D1. — P. D609–D617. — URL: https://doi.org/10.1093/nar/gkae1010
@article{bateman2024uniprot,
title = {{UniProt: the Universal Protein Knowledgebase in 2025}},
author = {Alex G. Bateman and Maria Jesus Martin and Sandra E. Orchard and Michele Magrane and Aduragbemi S. Adesina and Shadab Ahmad and Emily Bowler-Barnett and Hema Bye‐A‐Jee and David C. J. Carpentier and Paul Denny and Jun Fan and Penelope Garmiri and Leonardo Jose da Costa Gonzales and Abdulrahman Hussein and Alexandr Ignatchenko and Giuseppe Insana and Rizwan Ishtiaq and Vishal Joshi and Dushyanth Jyothi and Swaathi Kandasaamy and Antonia Lock and Aurélien Luciani and Jie Luo and Yvonne Lussi and Juan Marín and Pedro Raposo and Daniel L Rice and Rafael Silva Santos and Elena Speretta and James D. Stephenson and Prabhat Totoo and Nidhi Tyagi and Nadya Urakova and Preethi Vasudev and Kate Warner and Supun Wijerathne and Conny Wing-Heng Yu and Rossana Zaru and Alan James Bridge and Lucila Aimo and Ghislaine Argoud‐Puy and Andrea H Auchincloss and Kristian B. Axelsen and Parit Bansal and Delphine Baratin and Teresa M Batista Neto and Marie-Claude Blatter and Jerven Tjalling Bolleman and Emmanuel Boutet and Lionel Breuza and Blanca Cabrera Gil and Cristina Casals‐Casas and Kamal Chikh Echioukh and Elisabeth Coudert and Beatrice Cuche and Edouard de Castro and Anne Estreicher and Maria Livia Famiglietti and Marc Feuermann and Elisabeth Gasteiger and Pascale Gaudet and Sébastien Géhant and Vivienne Baillie Gerritsen and Arnaud Gos and Nadine M. Gruaz and Chantal Hulo and Nevila Hyka‐Nouspikel and Florence Jungo and Arnaud Kerhornou and Philippe Le Mercier and Damien Lieberherr and Patrick Masson and Anne Morgat and Salvo Paesano and Ivo Pedruzzi and Sandrine Pilbout and Lucille Pourcel and Sylvain Poux and Monica Pozzato and Manuela Pruess and Nicole Redaschi and Catherine Rivoire and Christian J A Sigrist and Karin Sonesson and Shyamala Sundaram and Anastasia Sveshnikova and Cathy H. Wu and Cecilia N. Arighi and Chuming Chen and Yongxing Chen and Hongzhan Huang and Kati Laiho and Minna Lehväslaiho and Peter B. McGarvey and Darren A. Natale and Karen E. ROSS and C R Vinayaka and Yuqi Wang and Jian Zhang},
journal = {Nucleic Acids Research},
year = {2024},
volume = {53},
number = {D1},
pages = {D609--D617},
doi = {10.1093/nar/gkae1010},
url = {https://doi.org/10.1093/nar/gkae1010}
}TY - JOUR AU - Bateman, Alex G. AU - Martin, Maria Jesus AU - Orchard, Sandra E. AU - Magrane, Michele AU - Adesina, Aduragbemi S. AU - Ahmad, Shadab AU - Bowler-Barnett, Emily AU - Bye‐A‐Jee, Hema AU - Carpentier, David C. J. AU - Denny, Paul AU - Fan, Jun AU - Garmiri, Penelope AU - Gonzales, Leonardo Jose da Costa AU - Hussein, Abdulrahman AU - Ignatchenko, Alexandr AU - Insana, Giuseppe AU - Ishtiaq, Rizwan AU - Joshi, Vishal AU - Jyothi, Dushyanth AU - Kandasaamy, Swaathi AU - Lock, Antonia AU - Luciani, Aurélien AU - Luo, Jie AU - Lussi, Yvonne AU - Marín, Juan AU - Raposo, Pedro AU - Rice, Daniel L AU - Santos, Rafael Silva AU - Speretta, Elena AU - Stephenson, James D. AU - Totoo, Prabhat AU - Tyagi, Nidhi AU - Urakova, Nadya AU - Vasudev, Preethi AU - Warner, Kate AU - Wijerathne, Supun AU - Yu, Conny Wing-Heng AU - Zaru, Rossana AU - Bridge, Alan James AU - Aimo, Lucila AU - Argoud‐Puy, Ghislaine AU - Auchincloss, Andrea H AU - Axelsen, Kristian B. AU - Bansal, Parit AU - Baratin, Delphine AU - Neto, Teresa M Batista AU - Blatter, Marie-Claude AU - Bolleman, Jerven Tjalling AU - Boutet, Emmanuel AU - Breuza, Lionel AU - Gil, Blanca Cabrera AU - Casals‐Casas, Cristina AU - Echioukh, Kamal Chikh AU - Coudert, Elisabeth AU - Cuche, Beatrice AU - Castro, Edouard de AU - Estreicher, Anne AU - Famiglietti, Maria Livia AU - Feuermann, Marc AU - Gasteiger, Elisabeth AU - Gaudet, Pascale AU - Géhant, Sébastien AU - Gerritsen, Vivienne Baillie AU - Gos, Arnaud AU - Gruaz, Nadine M. AU - Hulo, Chantal AU - Hyka‐Nouspikel, Nevila AU - Jungo, Florence AU - Kerhornou, Arnaud AU - Mercier, Philippe Le AU - Lieberherr, Damien AU - Masson, Patrick AU - Morgat, Anne AU - Paesano, Salvo AU - Pedruzzi, Ivo AU - Pilbout, Sandrine AU - Pourcel, Lucille AU - Poux, Sylvain AU - Pozzato, Monica AU - Pruess, Manuela AU - Redaschi, Nicole AU - Rivoire, Catherine AU - Sigrist, Christian J A AU - Sonesson, Karin AU - Sundaram, Shyamala AU - Sveshnikova, Anastasia AU - Wu, Cathy H. AU - Arighi, Cecilia N. AU - Chen, Chuming AU - Chen, Yongxing AU - Huang, Hongzhan AU - Laiho, Kati AU - Lehväslaiho, Minna AU - McGarvey, Peter B. AU - Natale, Darren A. AU - ROSS, Karen E. AU - Vinayaka, C R AU - Wang, Yuqi AU - Zhang, Jian TI - UniProt: the Universal Protein Knowledgebase in 2025 JO - Nucleic Acids Research VL - 53 IS - D1 SP - D609 EP - D617 PY - 2024 DA - 2024/10/16 DO - 10.1093/nar/gkae1010 UR - https://doi.org/10.1093/nar/gkae1010 ER -
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