- Published
- 2022-03-04
- Venue
- Periodontology 2000, vol. 89, no. 1, pp. 166-180
- Cited by
- 194
- Open access
- Yes, hybrid
- DOI
- 10.1111/prd.12426
- PubMed
- 35244982
Abstract
Accumulating evidence demonstrates that the oral pathobiont Fusobacterium nucleatum is involved in the progression of an increasing number of tumors types. Thus far, the mechanisms underlying tumor exacerbation by F. nucleatum include the enhancement of proliferation, establishment of a tumor-promoting immune environment, induction of chemoresistance, and the activation of immune checkpoints. This review focuses on the mechanisms that mediate tumor-specific colonization by fusobacteria. Elucidating the mechanisms mediating fusobacterial tumor tropism and promotion might provide new insights for the development of novel approaches for tumor detection and treatment.
Cite this paper
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- APA 7
Alon‐Maimon, T., Mandelboim, O., & Bachrach, G. (2022). Fusobacterium nucleatum and cancer. Periodontology 2000, 89(1), 166–180. https://doi.org/10.1111/prd.12426
- MLA 9
Alon‐Maimon, Tamar, et al. "Fusobacterium nucleatum and cancer." Periodontology 2000, vol. 89, no. 1, 2022, pp. 166–180, https://doi.org/10.1111/prd.12426.
- Chicago
Alon‐Maimon, Tamar, Ofer Mandelboim, and Gilad Bachrach. "Fusobacterium nucleatum and cancer." Periodontology 2000 89, no. 1 (2022): 166–180. https://doi.org/10.1111/prd.12426.
- GOST
Alon‐Maimon T., Mandelboim O., Bachrach G. Fusobacterium nucleatum and cancer // Periodontology 2000. — 2022. — Vol. 89, № 1. — P. 166–180. — URL: https://doi.org/10.1111/prd.12426
- BibTeX
@article{alonmaimon2022fusobacterium, title = {{Fusobacterium nucleatum and cancer}}, author = {Tamar Alon‐Maimon and Ofer Mandelboim and Gilad Bachrach}, journal = {Periodontology 2000}, year = {2022}, volume = {89}, number = {1}, pages = {166--180}, doi = {10.1111/prd.12426}, url = {https://doi.org/10.1111/prd.12426} }- RIS
TY - JOUR AU - Alon‐Maimon, Tamar AU - Mandelboim, Ofer AU - Bachrach, Gilad TI - Fusobacterium nucleatum and cancer JO - Periodontology 2000 VL - 89 IS - 1 SP - 166 EP - 180 PY - 2022 DA - 2022/03/04 DO - 10.1111/prd.12426 UR - https://doi.org/10.1111/prd.12426 ER -