- Published
- 2021-04-14
- Venue
- Science, vol. 372, no. 6544, pp. 821-826
- Cited by
- 342
- Open access
- Yes, hybrid
- DOI
- 10.1126/science.abh1558
- PubMed
- 33853971
Abstract
Unmitigated spread in Brazil Despite an extensive network of primary care availability, Brazil has suffered profoundly during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Using daily data from state health offices, Castro et al. analyzed the pattern of spread of COVID-19 cases and deaths in the country from February to October 2020. Clusters of deaths before cases became apparent indicated unmitigated spread. SARS-CoV-2 circulated undetected in Brazil for more than a month as it spread north from Sã o Paulo. In Manaus, transmission reached unprecedented levels after a momentary respite in mid-2020. Faria et al. tracked the evolution of a new, more aggressive lineage called P.1, which has 17 mutations, including three (K417T, E484K, and N501Y) in the spike protein. After a period of accelerated evolution, this variant emerged in Brazil during November 2020. Coupled with the emergence of P.1, disease spread was accelerated by stark local inequalities and political upheaval, which compromised a prompt federal response. Science , abh1558 and abh2644, this issue p. 821 and p. 815
Cite this paper
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- APA 7
Castro, M. C., Kim, S., Barberia, L., Ribeiro, A. F., Gurzenda, S., Ribeiro, K. B., Abbott, E., Blossom, J. C., Rache, B., & Singer, B. H. (2021). Spatiotemporal pattern of COVID-19 spread in Brazil. Science, 372(6544), 821–826. https://doi.org/10.1126/science.abh1558
- MLA 9
Castro, Márcia C., et al. "Spatiotemporal pattern of COVID-19 spread in Brazil." Science, vol. 372, no. 6544, 2021, pp. 821–826, https://doi.org/10.1126/science.abh1558.
- Chicago
Castro, Márcia C., Sun Kim, Lorena Barberia, Ana Freitas Ribeiro, Susie Gurzenda, Karina Braga Ribeiro, Erin Abbott, Jeffrey C. Blossom, Beatriz Rache, and Burton H. Singer. "Spatiotemporal pattern of COVID-19 spread in Brazil." Science 372, no. 6544 (2021): 821–826. https://doi.org/10.1126/science.abh1558.
- GOST
Castro M. C., Kim S., Barberia L. [и др.] Spatiotemporal pattern of COVID-19 spread in Brazil // Science. — 2021. — Vol. 372, № 6544. — P. 821–826. — URL: https://doi.org/10.1126/science.abh1558
- BibTeX
@article{castro2021spatiotemporal, title = {{Spatiotemporal pattern of COVID-19 spread in Brazil}}, author = {Márcia C. Castro and Sun Kim and Lorena Barberia and Ana Freitas Ribeiro and Susie Gurzenda and Karina Braga Ribeiro and Erin Abbott and Jeffrey C. Blossom and Beatriz Rache and Burton H. Singer}, journal = {Science}, year = {2021}, volume = {372}, number = {6544}, pages = {821--826}, doi = {10.1126/science.abh1558}, url = {https://doi.org/10.1126/science.abh1558} }- RIS
TY - JOUR AU - Castro, Márcia C. AU - Kim, Sun AU - Barberia, Lorena AU - Ribeiro, Ana Freitas AU - Gurzenda, Susie AU - Ribeiro, Karina Braga AU - Abbott, Erin AU - Blossom, Jeffrey C. AU - Rache, Beatriz AU - Singer, Burton H. TI - Spatiotemporal pattern of COVID-19 spread in Brazil JO - Science VL - 372 IS - 6544 SP - 821 EP - 826 PY - 2021 DA - 2021/04/14 DO - 10.1126/science.abh1558 UR - https://doi.org/10.1126/science.abh1558 ER -
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