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Mar Cabeza-Cabrerizo, Ana Cardoso, Carlos M. Minutti, Mariana Pereira da Costa, Caetano Reis e Sousa
Dendritic cells (DCs) possess the ability to integrate information about their environment and communicate it to other leukocytes, shaping adaptive and innate immunity. Over the years, a variety of cell types have been called DCs on the basis of phenotypic and functional attributes. Here, we refocus attention on conventional DCs (cDCs), a discrete cell lineage by ontogenetic and gene expression criteria that best corresponds to the cells originally described in the 1970s. We summarize current knowledge of mouse and human cDC subsets and describe their hematopoietic development and their phenotypic and functional attributes. We hope that our effort to review the basic features of cDC biology and distinguish cDCs from related cell types brings to the fore the remarkable properties of this cell type while shedding some light on the seemingly inordinate complexity of the DC field.
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Cabeza-Cabrerizo, M., Cardoso, A., Minutti, C. M., Costa, M. P. D., & Sousa, C. R. E. (2021). Dendritic Cells Revisited. Annual Review of Immunology, 39(1), 131–166. https://doi.org/10.1146/annurev-immunol-061020-053707
Cabeza-Cabrerizo, Mar, et al. "Dendritic Cells Revisited." Annual Review of Immunology, vol. 39, no. 1, 2021, pp. 131–166, https://doi.org/10.1146/annurev-immunol-061020-053707.
Cabeza-Cabrerizo, Mar, Ana Cardoso, Carlos M. Minutti, Mariana Pereira da Costa, and Caetano Reis e Sousa. "Dendritic Cells Revisited." Annual Review of Immunology 39, no. 1 (2021): 131–166. https://doi.org/10.1146/annurev-immunol-061020-053707.
Cabeza-Cabrerizo M., Cardoso A., Minutti C. M. [и др.] Dendritic Cells Revisited // Annual Review of Immunology. — 2021. — Vol. 39, № 1. — P. 131–166. — URL: https://doi.org/10.1146/annurev-immunol-061020-053707
@article{cabezacabrerizo2021dendritic,
title = {{Dendritic Cells Revisited}},
author = {Mar Cabeza-Cabrerizo and Ana Cardoso and Carlos M. Minutti and Mariana Pereira da Costa and Caetano Reis e Sousa},
journal = {Annual Review of Immunology},
year = {2021},
volume = {39},
number = {1},
pages = {131--166},
doi = {10.1146/annurev-immunol-061020-053707},
url = {https://doi.org/10.1146/annurev-immunol-061020-053707}
}TY - JOUR AU - Cabeza-Cabrerizo, Mar AU - Cardoso, Ana AU - Minutti, Carlos M. AU - Costa, Mariana Pereira da AU - Sousa, Caetano Reis e TI - Dendritic Cells Revisited JO - Annual Review of Immunology VL - 39 IS - 1 SP - 131 EP - 166 PY - 2021 DA - 2021/01/22 DO - 10.1146/annurev-immunol-061020-053707 UR - https://doi.org/10.1146/annurev-immunol-061020-053707 ER -
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