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Chiadi E. Ndumele, Janani Rangaswami, Sheryl L. Chow, Ian J. Neeland, Katherine R. Tuttle, Sadiya S. Khan, Josef Coresh, Roy O. Mathew, Carissa Marrie Baker-Smith, Mercedes R. Carnethon and 19 more
Cardiovascular-kidney-metabolic health reflects the interplay among metabolic risk factors, chronic kidney disease, and the cardiovascular system and has profound impacts on morbidity and mortality. There are multisystem consequences of poor cardiovascular-kidney-metabolic health, with the most significant clinical impact being the high associated incidence of cardiovascular disease events and cardiovascular mortality. There is a high prevalence of poor cardiovascular-kidney-metabolic health in the population, with a disproportionate burden seen among those with adverse social determinants of health. However, there is also a growing number of therapeutic options that favorably affect metabolic risk factors, kidney function, or both that also have cardioprotective effects. To improve cardiovascular-kidney-metabolic health and related outcomes in the population, there is a critical need for (1) more clarity on the definition of cardiovascular-kidney-metabolic syndrome; (2) an approach to cardiovascular-kidney-metabolic staging that promotes prevention across the life course; (3) prediction algorithms that include the exposures and outcomes most relevant to cardiovascular-kidney-metabolic health; and (4) strategies for the prevention and management of cardiovascular disease in relation to cardiovascular-kidney-metabolic health that reflect harmonization across major subspecialty guidelines and emerging scientific evidence. It is also critical to incorporate considerations of social determinants of health into care models for cardiovascular-kidney-metabolic syndrome and to reduce care fragmentation by facilitating approaches for patient-centered interdisciplinary care. This presidential advisory provides guidance on the definition, staging, prediction paradigms, and holistic approaches to care for patients with cardiovascular-kidney-metabolic syndrome and details a multicomponent vision for effectively and equitably enhancing cardiovascular-kidney-metabolic health in the population.
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Ndumele, C. E., Rangaswami, J., Chow, S. L., Neeland, I. J., Tuttle, K. R., Khan, S. S., Coresh, J., Mathew, R. O., Baker-Smith, C. M., Carnethon, M. R., Després, J., Ho, J. E., Joseph, J. J., Kernan, W. N., Khera, A., Kosiborod, M., Lekavich, C. L., Lewis, E. F., Lo, K. B., … Elkind, M. S. (2023). Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association. Circulation, 148(20), 1606–1635. https://doi.org/10.1161/cir.0000000000001184
Ndumele, Chiadi E., et al. "Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association." Circulation, vol. 148, no. 20, 2023, pp. 1606–1635, https://doi.org/10.1161/cir.0000000000001184.
Ndumele, Chiadi E., Janani Rangaswami, Sheryl L. Chow, Ian J. Neeland, Katherine R. Tuttle, Sadiya S. Khan, Josef Coresh, et al. "Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association." Circulation 148, no. 20 (2023): 1606–1635. https://doi.org/10.1161/cir.0000000000001184.
Ndumele C. E., Rangaswami J., Chow S. L. [и др.] Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association // Circulation. — 2023. — Vol. 148, № 20. — P. 1606–1635. — URL: https://doi.org/10.1161/cir.0000000000001184
@article{ndumele2023cardiovascularkidneymetabolic,
title = {{Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association}},
author = {Chiadi E. Ndumele and Janani Rangaswami and Sheryl L. Chow and Ian J. Neeland and Katherine R. Tuttle and Sadiya S. Khan and Josef Coresh and Roy O. Mathew and Carissa Marrie Baker-Smith and Mercedes R. Carnethon and Jean‐Pierre Després and Jennifer E. Ho and Joshua J. Joseph and Walter N. Kernan and Amit Khera and Mikhail Kosiborod and Carolyn L. Lekavich and Eldrin Foster Lewis and Kevin Bryan Lo and Bige Özkan and Latha P Palaniappan and Sonali S. Patel and Michael J. Pencina and Tiffany M. Powell‐Wiley and Laurence S. Sperling and Salim S. Virani and Jackson T. Wright and Radhika Rajgopal Singh and Mitchell S.V. Elkind},
journal = {Circulation},
year = {2023},
volume = {148},
number = {20},
pages = {1606--1635},
doi = {10.1161/cir.0000000000001184},
url = {https://doi.org/10.1161/cir.0000000000001184}
}TY - JOUR AU - Ndumele, Chiadi E. AU - Rangaswami, Janani AU - Chow, Sheryl L. AU - Neeland, Ian J. AU - Tuttle, Katherine R. AU - Khan, Sadiya S. AU - Coresh, Josef AU - Mathew, Roy O. AU - Baker-Smith, Carissa Marrie AU - Carnethon, Mercedes R. AU - Després, Jean‐Pierre AU - Ho, Jennifer E. AU - Joseph, Joshua J. AU - Kernan, Walter N. AU - Khera, Amit AU - Kosiborod, Mikhail AU - Lekavich, Carolyn L. AU - Lewis, Eldrin Foster AU - Lo, Kevin Bryan AU - Özkan, Bige AU - Palaniappan, Latha P AU - Patel, Sonali S. AU - Pencina, Michael J. AU - Powell‐Wiley, Tiffany M. AU - Sperling, Laurence S. AU - Virani, Salim S. AU - Wright, Jackson T. AU - Singh, Radhika Rajgopal AU - Elkind, Mitchell S.V. TI - Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association JO - Circulation VL - 148 IS - 20 SP - 1606 EP - 1635 PY - 2023 DA - 2023/10/09 DO - 10.1161/cir.0000000000001184 UR - https://doi.org/10.1161/cir.0000000000001184 ER -
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