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Praveen Dhyani, Cristina Quispe, Eshita Sharma, Amit Bahukhandi, Priyanka Sati, Dharam Chand Attri, Agnieszka Szopa, Javad Sharifi‐Rad, Anca Oana Docea, Ileana Mardare, Daniela Cornelia Călina, William Chi Shing Cho
Cancer, one of the leading illnesses, accounts for about 10 million deaths worldwide. The treatment of cancer includes surgery, chemotherapy, radiation therapy, and drug therapy, along with others, which not only put a tremendous economic effect on patients but also develop drug resistance in patients with time. A significant number of cancer cases can be prevented/treated by implementing evidence-based preventive strategies. Plant-based drugs have evolved as promising preventive chemo options both in developing and developed nations. The secondary plant metabolites such as alkaloids have proven efficacy and acceptability for cancer treatment. Apropos, this review deals with a spectrum of promising alkaloids such as colchicine, vinblastine, vincristine, vindesine, vinorelbine, and vincamine within different domains of comprehensive information on these molecules such as their medical applications (contemporary/traditional), mechanism of antitumor action, and potential scale-up biotechnological studies on an in-vitro scale. The comprehensive information provided in the review will be a valuable resource to develop an effective, affordable, and cost effective cancer management program using these alkaloids.
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Dhyani, P., Quispe, C., Sharma, E., Bahukhandi, A., Sati, P., Attri, D. C., Szopa, A., Sharifi‐Rad, J., Docea, A. O., Mardare, I., Călina, D. C., & Cho, W. C. S. (2022). Anticancer potential of alkaloids: a key emphasis to colchicine, vinblastine, vincristine, vindesine, vinorelbine and vincamine. Cancer Cell International, 22(1), 206. https://doi.org/10.1186/s12935-022-02624-9
Dhyani, Praveen, et al. "Anticancer potential of alkaloids: a key emphasis to colchicine, vinblastine, vincristine, vindesine, vinorelbine and vincamine." Cancer Cell International, vol. 22, no. 1, 2022, pp. 206, https://doi.org/10.1186/s12935-022-02624-9.
Dhyani, Praveen, Cristina Quispe, Eshita Sharma, Amit Bahukhandi, Priyanka Sati, Dharam Chand Attri, Agnieszka Szopa, et al. "Anticancer potential of alkaloids: a key emphasis to colchicine, vinblastine, vincristine, vindesine, vinorelbine and vincamine." Cancer Cell International 22, no. 1 (2022): 206. https://doi.org/10.1186/s12935-022-02624-9.
Dhyani P., Quispe C., Sharma E. [и др.] Anticancer potential of alkaloids: a key emphasis to colchicine, vinblastine, vincristine, vindesine, vinorelbine and vincamine // Cancer Cell International. — 2022. — Vol. 22, № 1. — P. 206. — URL: https://doi.org/10.1186/s12935-022-02624-9
@article{dhyani2022anticancer,
title = {{Anticancer potential of alkaloids: a key emphasis to colchicine, vinblastine, vincristine, vindesine, vinorelbine and vincamine}},
author = {Praveen Dhyani and Cristina Quispe and Eshita Sharma and Amit Bahukhandi and Priyanka Sati and Dharam Chand Attri and Agnieszka Szopa and Javad Sharifi‐Rad and Anca Oana Docea and Ileana Mardare and Daniela Cornelia Călina and William Chi Shing Cho},
journal = {Cancer Cell International},
year = {2022},
volume = {22},
number = {1},
pages = {206},
doi = {10.1186/s12935-022-02624-9},
url = {https://doi.org/10.1186/s12935-022-02624-9}
}TY - JOUR AU - Dhyani, Praveen AU - Quispe, Cristina AU - Sharma, Eshita AU - Bahukhandi, Amit AU - Sati, Priyanka AU - Attri, Dharam Chand AU - Szopa, Agnieszka AU - Sharifi‐Rad, Javad AU - Docea, Anca Oana AU - Mardare, Ileana AU - Călina, Daniela Cornelia AU - Cho, William Chi Shing TI - Anticancer potential of alkaloids: a key emphasis to colchicine, vinblastine, vincristine, vindesine, vinorelbine and vincamine JO - Cancer Cell International VL - 22 IS - 1 SP - 206 PY - 2022 DA - 2022/06/02 DO - 10.1186/s12935-022-02624-9 UR - https://doi.org/10.1186/s12935-022-02624-9 ER -
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