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Sizhe Liu, Vasiliy Galat, Yekaterina Galat, Yoo Kyung Annie Lee, Derek Alan Wainwright, Jennifer D. Wu
Natural killer (NK) cell is a specialized immune effector cell type that plays a critical role in immune activation against abnormal cells. Different from events required for T cell activation, NK cell activation is governed by the interaction of NK receptors with target cells, independent of antigen processing and presentation. Due to relatively unsophisticated cues for activation, NK cell has gained significant attention in the field of cancer immunotherapy. Many efforts are emerging for developing and engineering NK cell-based cancer immunotherapy. In this review, we provide our current understandings of NK cell biology, ongoing pre-clinical and clinical development of NK cell-based therapies and discuss the progress, challenges, and future perspectives.
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Liu, S., Galat, V., Galat, Y., Lee, Y. K. A., Wainwright, D. A., & Wu, J. D. (2021). NK cell-based cancer immunotherapy: from basic biology to clinical development. Journal of Hematology & Oncology, 14(1), 7. https://doi.org/10.1186/s13045-020-01014-w
Liu, Sizhe, et al. "NK cell-based cancer immunotherapy: from basic biology to clinical development." Journal of Hematology & Oncology, vol. 14, no. 1, 2021, pp. 7, https://doi.org/10.1186/s13045-020-01014-w.
Liu, Sizhe, Vasiliy Galat, Yekaterina Galat, Yoo Kyung Annie Lee, Derek Alan Wainwright, and Jennifer D. Wu. "NK cell-based cancer immunotherapy: from basic biology to clinical development." Journal of Hematology & Oncology 14, no. 1 (2021): 7. https://doi.org/10.1186/s13045-020-01014-w.
Liu S., Galat V., Galat Y. [и др.] NK cell-based cancer immunotherapy: from basic biology to clinical development // Journal of Hematology & Oncology. — 2021. — Vol. 14, № 1. — P. 7. — URL: https://doi.org/10.1186/s13045-020-01014-w
@article{liu2021cellbased,
title = {{NK cell-based cancer immunotherapy: from basic biology to clinical development}},
author = {Sizhe Liu and Vasiliy Galat and Yekaterina Galat and Yoo Kyung Annie Lee and Derek Alan Wainwright and Jennifer D. Wu},
journal = {Journal of Hematology \& Oncology},
year = {2021},
volume = {14},
number = {1},
pages = {7},
doi = {10.1186/s13045-020-01014-w},
url = {https://doi.org/10.1186/s13045-020-01014-w}
}TY - JOUR AU - Liu, Sizhe AU - Galat, Vasiliy AU - Galat, Yekaterina AU - Lee, Yoo Kyung Annie AU - Wainwright, Derek Alan AU - Wu, Jennifer D. TI - NK cell-based cancer immunotherapy: from basic biology to clinical development JO - Journal of Hematology & Oncology VL - 14 IS - 1 SP - 7 PY - 2021 DA - 2021/01/06 DO - 10.1186/s13045-020-01014-w UR - https://doi.org/10.1186/s13045-020-01014-w ER -
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