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Jian Liu, Minyang Fu, Manni Wang, Dandan Wan, Yuquan Wei, Xiawei Wei
Research on tumor immunotherapy has made tremendous progress in the past decades, with numerous studies entering the clinical evaluation. The cancer vaccine is considered a promising therapeutic strategy in the immunotherapy of solid tumors. Cancer vaccine stimulates anti-tumor immunity with tumor antigens, which could be delivered in the form of whole cells, peptides, nucleic acids, etc. Ideal cancer vaccines could overcome the immune suppression in tumors and induce both humoral immunity and cellular immunity. In this review, we introduced the working mechanism of cancer vaccines and summarized four platforms for cancer vaccine development. We also highlighted the clinical research progress of the cancer vaccines, especially focusing on their clinical application and therapeutic efficacy, which might hopefully facilitate the future design of the cancer vaccine.
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Liu, J., Fu, M., Wang, M., Wan, D., Wei, Y., & Wei, X. (2022). Cancer vaccines as promising immuno-therapeutics: platforms and current progress. Journal of Hematology & Oncology, 15(1), 28. https://doi.org/10.1186/s13045-022-01247-x
Liu, Jian, et al. "Cancer vaccines as promising immuno-therapeutics: platforms and current progress." Journal of Hematology & Oncology, vol. 15, no. 1, 2022, pp. 28, https://doi.org/10.1186/s13045-022-01247-x.
Liu, Jian, Minyang Fu, Manni Wang, Dandan Wan, Yuquan Wei, and Xiawei Wei. "Cancer vaccines as promising immuno-therapeutics: platforms and current progress." Journal of Hematology & Oncology 15, no. 1 (2022): 28. https://doi.org/10.1186/s13045-022-01247-x.
Liu J., Fu M., Wang M. [и др.] Cancer vaccines as promising immuno-therapeutics: platforms and current progress // Journal of Hematology & Oncology. — 2022. — Vol. 15, № 1. — P. 28. — URL: https://doi.org/10.1186/s13045-022-01247-x
@article{liu2022cancer,
title = {{Cancer vaccines as promising immuno-therapeutics: platforms and current progress}},
author = {Jian Liu and Minyang Fu and Manni Wang and Dandan Wan and Yuquan Wei and Xiawei Wei},
journal = {Journal of Hematology \& Oncology},
year = {2022},
volume = {15},
number = {1},
pages = {28},
doi = {10.1186/s13045-022-01247-x},
url = {https://doi.org/10.1186/s13045-022-01247-x}
}TY - JOUR AU - Liu, Jian AU - Fu, Minyang AU - Wang, Manni AU - Wan, Dandan AU - Wei, Yuquan AU - Wei, Xiawei TI - Cancer vaccines as promising immuno-therapeutics: platforms and current progress JO - Journal of Hematology & Oncology VL - 15 IS - 1 SP - 28 PY - 2022 DA - 2022/03/18 DO - 10.1186/s13045-022-01247-x UR - https://doi.org/10.1186/s13045-022-01247-x ER -
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