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Yifan Liu, Yushan Liang, Jing Yuhong, Peng Xin, Jia Han, Yongle Du, Xinru Yu, Runhe Zhu, Mingxun Zhang, Wen Chen, Yingjie Ma
This manuscript offers a comprehensive overview of nanotechnology's impact on the solubility and bioavailability of poorly soluble drugs, with a focus on BCS Class II and IV drugs. We explore various nanoscale drug delivery systems (NDDSs), including lipid-based, polymer-based, nanoemulsions, nanogels, and inorganic carriers. These systems offer improved drug efficacy, targeting, and reduced side effects. Emphasizing the crucial role of nanoparticle size and surface modifications, the review discusses the advancements in NDDSs for enhanced therapeutic outcomes. Challenges such as production cost and safety are acknowledged, yet the potential of NDDSs in transforming drug delivery methods is highlighted. This contribution underscores the importance of nanotechnology in pharmaceutical engineering, suggesting it as a significant advancement for medical applications and patient care.
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Liu, Y., Liang, Y., Yuhong, J., Xin, P., Han, J., Du, Y., Yu, X., Zhu, R., Zhang, M., Chen, W., & Ma, Y. (2024). Advances in Nanotechnology for Enhancing the Solubility and Bioavailability of Poorly Soluble Drugs. Drug Design Development and Therapy, Volume 18, 1469–1495. https://doi.org/10.2147/dddt.s447496
Liu, Yifan, et al. "Advances in Nanotechnology for Enhancing the Solubility and Bioavailability of Poorly Soluble Drugs." Drug Design Development and Therapy, vol. Volume 18, 2024, pp. 1469–1495, https://doi.org/10.2147/dddt.s447496.
Liu, Yifan, Yushan Liang, Jing Yuhong, Peng Xin, Jia Han, Yongle Du, Xinru Yu, et al. "Advances in Nanotechnology for Enhancing the Solubility and Bioavailability of Poorly Soluble Drugs." Drug Design Development and Therapy Volume 18 (2024): 1469–1495. https://doi.org/10.2147/dddt.s447496.
Liu Y., Liang Y., Yuhong J. [и др.] Advances in Nanotechnology for Enhancing the Solubility and Bioavailability of Poorly Soluble Drugs // Drug Design Development and Therapy. — 2024. — Vol. Volume 18. — P. 1469–1495. — URL: https://doi.org/10.2147/dddt.s447496
@article{liu2024advances,
title = {{Advances in Nanotechnology for Enhancing the Solubility and Bioavailability of Poorly Soluble Drugs}},
author = {Yifan Liu and Yushan Liang and Jing Yuhong and Peng Xin and Jia Han and Yongle Du and Xinru Yu and Runhe Zhu and Mingxun Zhang and Wen Chen and Yingjie Ma},
journal = {Drug Design Development and Therapy},
year = {2024},
volume = {Volume 18},
pages = {1469--1495},
doi = {10.2147/dddt.s447496},
url = {https://doi.org/10.2147/dddt.s447496}
}TY - JOUR AU - Liu, Yifan AU - Liang, Yushan AU - Yuhong, Jing AU - Xin, Peng AU - Han, Jia AU - Du, Yongle AU - Yu, Xinru AU - Zhu, Runhe AU - Zhang, Mingxun AU - Chen, Wen AU - Ma, Yingjie TI - Advances in Nanotechnology for Enhancing the Solubility and Bioavailability of Poorly Soluble Drugs JO - Drug Design Development and Therapy VL - Volume 18 SP - 1469 EP - 1495 PY - 2024 DA - 2024/05/01 DO - 10.2147/dddt.s447496 UR - https://doi.org/10.2147/dddt.s447496 ER -
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