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Menglong Wang, Wei Dong Pan, Xu Yao, Jishou Zhang, Jun Wan, Hong Jiang
Microglia are tissue-resident macrophages of the central nervous system (CNS). In the CNS, microglia play an important role in the monitoring and intervention of synaptic and neuron-level activities. Interventions targeting microglia have been shown to improve the prognosis of various neurological diseases. Recently, studies have observed the activation of microglia in different cardiovascular diseases. In addition, different approaches that regulate the activity of microglia have been shown to modulate the incidence and progression of cardiovascular diseases. The change in autonomic nervous system activity after neuroinflammation may be a potential intermediate link between microglia and cardiovascular diseases. Here, in this review, we will discuss recent updates on the regulatory role of microglia in hypertension, myocardial infarction and ischemia/reperfusion injury. We propose that microglia serve as neuroimmune modulators and potential targets for cardiovascular diseases.
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Wang, M., Pan, W. D., Yao, X., Zhang, J., Wan, J., & Jiang, H. (2022). Microglia-Mediated Neuroinflammation: A Potential Target for the Treatment of Cardiovascular Diseases. Journal of Inflammation Research, Volume 15, 3083–3094. https://doi.org/10.2147/jir.s350109
Wang, Menglong, et al. "Microglia-Mediated Neuroinflammation: A Potential Target for the Treatment of Cardiovascular Diseases." Journal of Inflammation Research, vol. Volume 15, 2022, pp. 3083–3094, https://doi.org/10.2147/jir.s350109.
Wang, Menglong, Wei Dong Pan, Xu Yao, Jishou Zhang, Jun Wan, and Hong Jiang. "Microglia-Mediated Neuroinflammation: A Potential Target for the Treatment of Cardiovascular Diseases." Journal of Inflammation Research Volume 15 (2022): 3083–3094. https://doi.org/10.2147/jir.s350109.
Wang M., Pan W. D., Yao X. [и др.] Microglia-Mediated Neuroinflammation: A Potential Target for the Treatment of Cardiovascular Diseases // Journal of Inflammation Research. — 2022. — Vol. Volume 15. — P. 3083–3094. — URL: https://doi.org/10.2147/jir.s350109
@article{wang2022microgliamediated,
title = {{Microglia-Mediated Neuroinflammation: A Potential Target for the Treatment of Cardiovascular Diseases}},
author = {Menglong Wang and Wei Dong Pan and Xu Yao and Jishou Zhang and Jun Wan and Hong Jiang},
journal = {Journal of Inflammation Research},
year = {2022},
volume = {Volume 15},
pages = {3083--3094},
doi = {10.2147/jir.s350109},
url = {https://doi.org/10.2147/jir.s350109}
}TY - JOUR AU - Wang, Menglong AU - Pan, Wei Dong AU - Yao, Xu AU - Zhang, Jishou AU - Wan, Jun AU - Jiang, Hong TI - Microglia-Mediated Neuroinflammation: A Potential Target for the Treatment of Cardiovascular Diseases JO - Journal of Inflammation Research VL - Volume 15 SP - 3083 EP - 3094 PY - 2022 DA - 2022/05/01 DO - 10.2147/jir.s350109 UR - https://doi.org/10.2147/jir.s350109 ER -
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