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Christopher G. Laine, Valen E. Johnson, Harvey Morgan Scott, Ángela M. Arenas-Gamboa
Brucellosis is a major public health concern worldwide, especially for persons living in resource-limited settings. Historically, an evidence-based estimate of the global annual incidence of human cases has been elusive. We used international public health data to fill this information gap through application of risk metrics to worldwide and regional at-risk populations. We performed estimations using 3 statistical models (weighted average interpolation, bootstrap resampling, and Bayesian inference) and considered missing information. An evidence-based conservative estimate of the annual global incidence is 2.1 million, significantly higher than was previously assumed. Our models indicate Africa and Asia sustain most of the global risk and cases, although areas within the Americas and Europe remain of concern. This study reveals that disease risk and incidence are higher than previously suggested and lie mainly within resource-limited settings. Clarification of both misdiagnosis and underdiagnosis is required because those factors will amplify case estimates.
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Laine, C. G., Johnson, V. E., Scott, H. M., & Arenas-Gamboa, Á. M. (2023). Global Estimate of Human Brucellosis Incidence. Emerging infectious diseases, 29(9), 1789–1797. https://doi.org/10.3201/eid2909.230052
Laine, Christopher G., et al. "Global Estimate of Human Brucellosis Incidence." Emerging infectious diseases, vol. 29, no. 9, 2023, pp. 1789–1797, https://doi.org/10.3201/eid2909.230052.
Laine, Christopher G., Valen E. Johnson, Harvey Morgan Scott, and Ángela M. Arenas-Gamboa. "Global Estimate of Human Brucellosis Incidence." Emerging infectious diseases 29, no. 9 (2023): 1789–1797. https://doi.org/10.3201/eid2909.230052.
Laine C. G., Johnson V. E., Scott H. M. [и др.] Global Estimate of Human Brucellosis Incidence // Emerging infectious diseases. — 2023. — Vol. 29, № 9. — P. 1789–1797. — URL: https://doi.org/10.3201/eid2909.230052
@article{laine2023global,
title = {{Global Estimate of Human Brucellosis Incidence}},
author = {Christopher G. Laine and Valen E. Johnson and Harvey Morgan Scott and Ángela M. Arenas-Gamboa},
journal = {Emerging infectious diseases},
year = {2023},
volume = {29},
number = {9},
pages = {1789--1797},
doi = {10.3201/eid2909.230052},
url = {https://doi.org/10.3201/eid2909.230052}
}TY - JOUR AU - Laine, Christopher G. AU - Johnson, Valen E. AU - Scott, Harvey Morgan AU - Arenas-Gamboa, Ángela M. TI - Global Estimate of Human Brucellosis Incidence JO - Emerging infectious diseases VL - 29 IS - 9 SP - 1789 EP - 1797 PY - 2023 DA - 2023/08/23 DO - 10.3201/eid2909.230052 UR - https://doi.org/10.3201/eid2909.230052 ER -
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