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Faraedon Mohidden Mostafa Zardawi, Sarhang Sarwat Gul, Ali Abbas Abdulkareem, Aram Mohammed Sha, Julian M. Yates
Atherosclerotic cardiovascular disease (ACVD) is an inflammatory disease of the coronary arteries associated with atheroma formation, which can cause disability and often death. Periodontitis is ranked as the sixth most prevalent disease affecting humans affecting 740 million people worldwide. In the last few decades, researchers have focused on the effect of periodontal disease (PD) on cardiovascular disease. The aim of this review was to investigate the association between these two diseases. PD is a potential risk factor that may initiate the development, maturation, and instability of atheroma in the arteries. Two mechanisms were proposed to explain such association, either periodontal pathogens directly invade bloodstream or indirectly by increasing systemic level of inflammatory mediators. Interestingly, it has been suggested that improvement in the condition of one disease positively impact the condition of the other one. Highlighting the association between these two diseases, the importance of early diagnosis and treatment of PD and its impact on cardiovascular status may be of great value in reducing the complications associated with ACVDs. Further in vitro and in vivo studies with longer follow up are necessary to confirm the causal relationship between PD and ACVDs.
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Zardawi, F. M. M., Gul, S. S., Abdulkareem, A. A., Sha, A. M., & Yates, J. M. (2021). Association Between Periodontal Disease and Atherosclerotic Cardiovascular Diseases: Revisited. Frontiers in Cardiovascular Medicine, 7, 625579. https://doi.org/10.3389/fcvm.2020.625579
Zardawi, Faraedon Mohidden Mostafa, et al. "Association Between Periodontal Disease and Atherosclerotic Cardiovascular Diseases: Revisited." Frontiers in Cardiovascular Medicine, vol. 7, 2021, pp. 625579, https://doi.org/10.3389/fcvm.2020.625579.
Zardawi, Faraedon Mohidden Mostafa, Sarhang Sarwat Gul, Ali Abbas Abdulkareem, Aram Mohammed Sha, and Julian M. Yates. "Association Between Periodontal Disease and Atherosclerotic Cardiovascular Diseases: Revisited." Frontiers in Cardiovascular Medicine 7 (2021): 625579. https://doi.org/10.3389/fcvm.2020.625579.
Zardawi F. M. M., Gul S. S., Abdulkareem A. A. [и др.] Association Between Periodontal Disease and Atherosclerotic Cardiovascular Diseases: Revisited // Frontiers in Cardiovascular Medicine. — 2021. — Vol. 7. — P. 625579. — URL: https://doi.org/10.3389/fcvm.2020.625579
@article{zardawi2021association,
title = {{Association Between Periodontal Disease and Atherosclerotic Cardiovascular Diseases: Revisited}},
author = {Faraedon Mohidden Mostafa Zardawi and Sarhang Sarwat Gul and Ali Abbas Abdulkareem and Aram Mohammed Sha and Julian M. Yates},
journal = {Frontiers in Cardiovascular Medicine},
year = {2021},
volume = {7},
pages = {625579},
doi = {10.3389/fcvm.2020.625579},
url = {https://doi.org/10.3389/fcvm.2020.625579}
}TY - JOUR AU - Zardawi, Faraedon Mohidden Mostafa AU - Gul, Sarhang Sarwat AU - Abdulkareem, Ali Abbas AU - Sha, Aram Mohammed AU - Yates, Julian M. TI - Association Between Periodontal Disease and Atherosclerotic Cardiovascular Diseases: Revisited JO - Frontiers in Cardiovascular Medicine VL - 7 SP - 625579 PY - 2021 DA - 2021/01/15 DO - 10.3389/fcvm.2020.625579 UR - https://doi.org/10.3389/fcvm.2020.625579 ER -
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